Familiar opposition for Arsenal and Chelsea when Champions League resumes in February, while Man City can be confident of making maiden quarter-finals.
Chelsea have been paired with Paris Saint-Germain in a Champions League knockout tie for the third successive season following this term’s last 16 draw.
BT Sport will be showing all eight two-legged ties as part of their thoroughgoing coverage of Europe’s top club competition, which resumes on Tuesday, February 16.
The first legs will take place on that and three other dates (February 17, 23 and 24), with the return fixtures on March 8, 9, 15 and 16.
Blues boss Jose Mourinho has lost just one of six meetings with PSG across his two spells at Stamford Bridge, but last season was eliminated at this stage of the Champions League by Laurent Blanc’s boys on away goals. Ladbrokes offer the top price for Chelsea to repeat their 2012 success and lift the trophy at 22/1.
In stark contrast to that above stat on Mourinho, Arsene Wenger has beaten Arsenal’s last 16 opponents Barcelona on a sole occasion from seven attempts. The Gunners lost the 2006 final to Catalan giants Barca and they been the most successful Champions League team since, recording three further triumphs in the last nine seasons.
Arsenal, now holding best odds of 40/1 with bet365 for European glory, are paying the price for their poor start to their European campaign by battling outright favourites Barcelona, as Wenger’s men finished behind Bayern Munich in their group.
It would be bold and brave to back the Gunners getting past Barca, who boast sensational South American front three Lionel Messi, Neymar and Luis Suarez. They fired the Nou Camp club to the Champions League last season, and 888Sport make Luis Enrique’s team a top-price 13/5 to retain the trophy.
Manchester City, meanwhile, will feel confident of advancing to the last eight for the first time, as they have drawn Ukrainian outfit Dynamo Kiev.
Manuel Pellegrini cannot afford to adopt too casual an approach to this tie, however, as the Etihad outfit were dumped out of the Europa League by this opposition in 2011 under predecessor Roberto Mancini. City lost the away leg 2-0 in Kiev and could only halve the deficit at home.
While war-torn Ukraine remains a hostile place for Man City to go, the strength in depth of their squad makes them an intriguing outright shout at best odds of 12/1 with Betway. Dynamo were perhaps fortunate to pip Porto to second spot behind Chelsea in their pool, and that should tell here.
Away from Premier League interest, Real Madrid and Roma meet for just the second time in the knockout phase with the Giallorossi winning 2-1 both home and away in the last 16 back in 2008. Long-serving Bernabeu defenders Pepe and Sergio Ramos could face Roman icon Francesco Totti once again.
Pep Gaurdiola, meanwhile, will fancy his chances of a third Champions League success as a coach, as his Bayern Munich side battle last term’s beaten finalists Juventus – now much diminished by the loss of experienced players from their spine.
The Old Lady have let playmaker Andrea Pirlo and striker Carlos Tevez go, as well as Arturo Vidal who now faces his former club, with hopes pinned on Paul Pogba producing some midfield magic.
Bayern, who are 11/4 with a raft of bookmakers including William Hill to lift the European Cup, will believe they can outclass Juve as they did in the 2013 quarter-finals when they won 2-0 home and away en route to a historic Bundesliga, DFB Pokal and Champions League treble.
Ties between Atletico Madrid and PSV Eindhoven, Benfica and Zenit St Petersburg, and first-time qualifiers Ghent and Wolfsburg complete this season’s Champions League last 16 line-up.
Champions League 2015/16 last 16 fixtures
All ties live on BT Sport at 19:45 on the below dates:
First leg matches
Tuesday, February 16
Paris Saint-Germain v Chelsea; Parc des Princes, Paris
Benfica v Zenit St Petersburg; Estadio da Luz, Lisbon
Wednesday, February 17
Ghent v Wolfsburg; Ghelamco Arena, Ghent
Roma v Real Madrid; Stadio Olimpico, Rome
Tuesday, February 23
Arsenal v Barcelona; Emirates Stadium, London
Juventus v Bayern Munich; Juventus Stadium, Turin
Wednesday, February 24
PSV Eindhoven v Atletico Madrid; Philips Stadion, Eindhoven
Dynamo Kiev v Manchester City; Olympic Stadium, Kiev
Second leg matches
Tuesday, March 8
Real Madrid v Roma; Estadio Santiago Bernabeu, Madrid
Wolfsburg v Ghent; Wolkswagen Arena, Wolfsburg
Wednesday, March 9
Chelsea v Paris Saint-Germain; Stamford Bridge, London
Zenit St Petersburg v Benfica; Petrovsky Stadium, St Petersburg
Tuesday, March 15
Manchester City v Dynamo Kiev; Etihad Stadium, Manchester
Atletico Madrid v PSV Eindhoven; Estadio Vicente Calderon, Madrid
Wednesday, March 16
Barcelona v Arsenal; Nou Camp, Barcelona
Bayern Munich v Juventus; Allianz Arena, Munich
Champions League quarter-finals and semi-finals draw dates and schedule
Quarter-final draw: Friday, March 18th
Quarter-final first leg fixtures: Tuesday, April 5 and Wednesday, April 6
Quarter-final second leg fixtures: Tuesday, April 12 and Wednesday, April 13
Semi-final draw: Friday, April 15
Semi-final first leg fixtures: Tuesday, April 26 and Wednesday, April 27
Semi-final second leg fixtures: Tuesday, May 3 and Wednesday, May 4
Champions League final: Saturday, May 28
All odds were correct at time of posting.