Eytan Shander for Bookies.com

By Eytan Shander | | 3 mins

NFL Week 16 Odds & Lines: Early Look at Top Matchups, Schedule

NFL Week 16 Odds & Lines: Early Look at Top Matchups, Schedule
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We hit a fun stretch of the NFL schedule, starting with a mash-up of days in Week 16. With short weeks two times over, we will see NFL betting treat those games like primetime affairs. The return of Saturday NFL Football should make an increase for betting sites on both games and heavy action on NFL Week 16 odds. Making NFL picks this deep in the season is never easy, so pay attention to injuries.

The 49ers and Titans open the week in Nashville. Then it’s two games on Saturday, Christmas Day, as the Packers host the Browns and the Colts take on the Cardinals. Sunday NFL Week 16 lines are highlighted the Ravens and Bengals in Cincinnati and Bills at the Patriots. The Dolphins and Saints close out the week on Monday Night Football.

Could New York sports betting sites be live in time for Christmas? It would be a great gift for The Empire State.

Note: Sportsbooks will release NFL Week 16 Odds closer to NFL Week 16. Be sure to bookmark this page and check back for the NFL odds from top betting apps as they become available.

NFL Week 16 Schedule

For games December 23-27

  • San Francisco 49ers at Tennessee Titans, 8:20 p.m. ET (TNF)
  • Cleveland Browns at Green Bay Packers, 4:30 p.m. ET (Saturday)
  • Indianapolis Colts at Arizona Cardinals, 8:15 p.m. ET (Saturday)
  • Baltimore Ravens at Cincinnati Bengals, 1 p.m. ET
  • Buffalo Bills at New England Patriots, 1 p.m. ET
  • Detroit Lions at Atlanta Falcons, 1 p.m. ET
  • Jacksonville Jaguars at New York Jets, 1 p.m. ET
  • Los Angeles Chargers at Houston Texans, 1 p.m. ET
  • Los Angeles Rams at Minnesota Vikings, 1 p.m. ET
  • New York Giants at Philadelphia Eagles, 1 p.m. ET
  • Tampa Bay Bucs at Carolina Panthers, 1 p.m. ET
  • Chicago Bears at Seattle Seahawks, 4:05 p.m. ET
  • Denver Broncos at Las Vegas Raiders, 4:25 p.m. ET
  • Pittsburgh Steelers at Kansas City Chiefs, 4:25 p.m. ET
  • Washington Football Team at Dallas Cowboys, 8:20 p.m. ET (SNF)
  • Miami Dolphins at New Orleans Saints, 8:15 p.m. ET (MNF)
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Thursday Night Football

San Francisco 49ers at Tennessee Titans, 8:20 p.m. ET 12/23

The Niners had to battle through a lot of early season injuries as they hit the road to take on the Titans. Nashville was buzzing early in the season with the hopes of Derrick Henry winning the MVP, as the team returns home following a road game against Pittsburgh. The Niners are also coming off a short week, but doing so at home after playing the Falcons

Sunday Night Football

Washington Football Team at Dallas Cowboys 8:20 p.m. ET

We remember when Washington playing Dallas meant something. This NFC East battle could easily get flexed out for a more compelling game – perhaps Buffalo at New England.

Monday Night Football

Miami Dolphins at New Orleans Saints 8:15 p.m. ET 12/27

A rare Monday night matchup between the Dolphins and Saints winds down the week in New Orleans. It’s the second primetime game in as many weeks for the Saints as they come off a SNF appearance in Tampa Bay. For the Dolphins, they hit the road for this game after hosting the Jets in Week 15. Louisiana sports betting and Florida sports betting should both be online for this showdown.

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About the Author

Eytan Shander for Bookies.com
Eytan Shander
Eytan Shander writes about the NFL, NBA and more for Bookies.com. A 15-year radio veteran, he has worked nationally for Mad Dog Radio & NBC Sports Radio.