Adam Thompson for

By Adam Thompson | | 13 mins

NFL Week 7 Odds: Spreads, Moneylines, Totals for Every Game

NFL Week 7 Odds: Spreads, Moneylines, Totals for Every Game

Up to $5,000 Risk-Free Bet - Promo Code: BOOKIES

Bet Now

Marquee matchups aren’t the headline when examining NFL Week 7 odds across betting sites. There isn’t that one shining game atop the schedule. What there is, however, is NFL betting intrigue.

A number of teams will learn where they really stand when the smoke clears from Week 7.

It starts in Nashville, where the NFL’s most-dominant back three years running, Derrick Henry, faces Patrick Mahomes and a Kansas City Chiefs team that is in a fight to contend for their own division. Joe Burrow and the upstart Cincinnati Bengals face the AFC North power Baltimore Ravens with Lamar Jackson, and the Las Vegas Raiders see if they can salvage their season when they face Jalen Hurts and the meandering Philadelphia Eagles – a huge game for both sides.

There’s a ton to consider when making your NFL picks. Here’s our early look:

Opening NFL Week 7 Odds vs Current Spreads

How have the Week 7 NFL odds changed on betting apps since they were released? Here are the opening and current NFL Week 7 betting lines via DraftKings Sportsbook.

Game matchupOpening SpreadCurrent Spread
Denver Broncos at Cleveland Browns Browns -6Browns -2
Cincinnati Bengals at Baltimore Ravens Bengals -6.5Bengals -6.5
Atlanta Falcons at Miami DolphinsDolphins -2.5Dolphins -2.5
Washington Football Team at Green Bay PackersPackers -7Packers -7.5
New York Jets at New England Patriots Patriots -7Patriots -7
Carolina Panthers at New York Giants Panthers -2.5Panthers -3
Kansas City Chiefs at Tennessee Titans Chiefs -3.5Chiefs -5.5
Detroit Lions at Los Angeles Rams Rams -13.5Rams -14.5
Philadelphia Eagles at Las Vegas Raiders Raiders -2.5Raiders -3
Houston Texans at Arizona Cardinals Cardinals -14Cardinals -17.5
Chicago Bears at Tampa Bay Buccaneers Buccaneers -10Buccaneers -12
Indianapolis Colts at San Francisco 49ers 49ers -549ers -4.5
New Orleans Saints at Seattle Seahawks Saints -3.5Saints -4.5

Bet $1 Get $200 NFL Special plus 20% Deposit Bonus up to $1,000

Bet Now

Thursday, Oct. 21

Denver Broncos at Cleveland Browns (-2), 8:20 p.m. ET

Denver’s offense remains a work in progress, but it took a step back vs. a mediocre Raiders defense in Week 6. Teddy Bridgewater averaged just 6.8 yards per attempt, and four turnovers were critical in a 34-24 home loss. A Broncos defense that ranked in the top 6 vs. both the run and the pass was eaten up by Derek Carr.

The Browns defense was rolled for 47 points by the Chargers in Week 5, then for 37 more in Week 6 by the Cardinals. And now the offense has become a mangled mess of injuries. Star RB Nick Chubb didn’t play last Sunday and is out for Thursday. So is QB Baker Mayfield, meaning Case Keenum is starting. WR Odell Beckham Jr. and both starting tackles are questionable, too. Defensively, the team still ranks in the top 10, and Denver doesn’t have the firepower of those two previous matchups.

Take a look at Broncos vs Browns odds, injury report, betting lines and more.

Sunday, Oct. 24

Carolina Panthers (-3) at New York Giants, 1 p.m. ET

Carolina’s defense, which ranked No. 2 in yards allowed going into Week 6, surrendered 571 yards to the Vikings in a home OT loss. After a hot start, Sam Darnold has certainly cooled off. He now has seven TDs with seven INTs, and star RB Christian McCaffrey is out at least two more weeks.

A decimated Giants lineup has been missing key parts of every level of offense. That includes RB Saquon Barkley, the top three wideouts on the depth chart and a QB (Daniel Jones) who was in concussion protocol all week. Unfortunately, the Giants defense isn’t helping, allowing over 400 yards per game. Neither side looked competitive in a 38-11 home beatdown at the hands of the Rams. Daniel Jones played but tossed three INTs.

Take a look at Panthers vs Giants odds, injury report, betting lines and more.

New York Jets at New England Patriots (-7), 1 p.m. ET

The Jets have lost 11 in a row to the Patriots, and most haven’t been particularly close. Of course, most of those were against Tom Brady. There’s reason to be optimistic for an offense that’s scored 27 and 20 points the last two weeks after scoring 20 in the previous three weeks combined.

It was hard to argue with a Patriots defense that ranked fifth through five weeks. But Week 6 was a different story, as Dak Prescott passed for 445 yards and a game-winning TD in overtime. The Jets don’t have the arsenal of the Cowboys, however. New England is 2-1 when its offense scores over a modest 17 points.

Take a look at Patriots vs Jets odds, injury report, betting lines and more.


Risk Free Bet up to $1,000 - Promo Code: BOOKIES

Bet Now

Kansas City Chiefs (-5.5) at Tennessee Titans, 1 p.m. ET

The sailing hasn’t been smooth for Patrick Mahomes and the Chiefs, the defending AFC champions. But both sides looked solid enough in a 31-13 win at Washington in Week 6. Mahomes passed for 397 yards, with two TDs and two INTs, and the defense kept WFT to just one TD. The offense has never finished lower than sixth in scoring with Mahomes at QB.

Derrick Henry has averaged 145.5 yards rushing over the last four games. The Chiefs have allowed at least 120 yards rushing in three of their five games. The wonder is if a Titans defense that allowed 454 yards to the Jaguars in Week 5 can do its part.

Take a look at Chiefs vs Titans odds, injury report, betting lines and more.

Washington Football Team at Green Bay Packers (-7.5), 1 p.m. ET

Washington’s defense, the best at stopping the pass in 2020, ranks in the bottom five in that category this year – bad news as they head to Lambeau. The unit just got mauled for 397 pass yards vs. Patrick Mahomes and the Chiefs in Week 6. Taylor Heinicke passed for only 182 yards vs. a KC defense that ranks poorly across the board.

The Packers scored only three points in their opener but have scored 28 ppg since then, all in winning efforts. Aaron Rodgers tossed for only 195 yards vs. a strong Bears defense in Week 6, but passed for two TDs and ran for another. The Packers’ run game averaged 5.0 yards per carry and 155 yards in total. One red flag: The Packers red zone defense has allowed a TD in every opposing possession.

Take a look at Washington vs Packers odds, injury report, betting lines and more.

Atlanta Falcons at Miami Dolphins (-2.5), 1 p.m. ET

After a dreadful opening two weeks of the NFL season, the Falcons went 2-1 before a Week 6 bye. Despite ranking 28th in points allowed, Atlanta is a solid 12th in yards allowed. The discrepancy is due to ill-timed turnovers, including a pair of Week 1 Pick 6’s.

The Dolphins went to London, and questionable coaching decisions helped hand the Jaguars their first win in nearly two years. One bright spot: The offense welcomed back QB Tua Tagovailoa and it made a difference; the Dolphins had 431 total yards after accumulating over 301 yards just one other time this year.

Take a look at Falcons at Dolphins odds, injury report, betting lines and more.


$1,000 Risk-Free First Bet

Bet Now

Cincinnati Bengals at Baltimore Ravens (-6.5), 1 p.m. ET

Joe Burrow tossed for three TDs and 271 yards and the run game rolled for 139 as the Bengals improved to 4-2 with a dominating win over the Lions in Week 6. The defense was just as impressive, shutting out the Lions until the game was well in hand. The Bengals’ D rank in the top 10 in yards allowed, a feat it hasn’t done in a full season since 2013.

The Ravens hadn’t been their dominant selves, but that changed in Week 6 in a rousing 34-6 rout of the surging Chargers. They held Justin Herbert and the vaunted L.A. offense to 208 total yards while three different Ravens had rushing TDs, and none of them were Lamar Jackson. Baltimore has beaten Cincinnati five straight times, the last three each by 24 or more points.

Take a look at Bengals vs Ravens odds, injury report, betting lines and more.

Philadelphia Eagles at Las Vegas Raiders (-3), 4:05 p.m. ET

Eagles QB Jalen Hurts faced the NFL’s worst-ranked pass defense last Thursday and went 12-of-26 for 115 yards in a home loss to the Buccaneers. The defense still ranks in the top five vs. the pass despite the 297 put upon them by Tom Brady.

The first game under interim coach Rich Bisaccia couldn’t have gone much better in a 34-24 victory of the Broncos in Denver. The offense had managed just 23 points in the previous two games combined but Derek Carr rebounded nicely. Even more impressive, the Las Vegas defense limited Denver (10 points until fourth-quarter garbage time) after allowing 25.3 ppg to the Dolphins, Chargers and Bears the last three weeks.

Take a look at Raiders vs Eagles odds, injury report, betting lines and more.

Detroit Lions at Los Angeles Rams (-14.5), 4:05 p.m. ET

The bad got worse for the winless Lions in a 34-11 home beatdown at the hands of the Bengals in Week 6. Jared Goff has the lowest QBR of any starter that isn’t a rookie and the offense hasn’t scored more than 17 points since Week 1.

Matthew Stafford faces his longtime former team, so there is added motivation for an offense that ranks third in passing and top 10 overall in yards and points. The offense has scored at least 26 points in every game this season – against better defenses than the one coming to L.A. here. Meanwhile, the Rams defense forced four turnovers in Week 6. Sportsbooks have the Rams as one of the biggest favorites in Week 7 odds.

Take a look at Rams vs Lions odds, injury report, betting lines and more.


Risk Free Bet up to $1,000
To Claim: Click Bet Now

Bet Now

Houston Texans at Arizona Cardinals (-17.5), 4:25 p.m. ET

Houston’s offense has been a disaster, and that didn’t change in Week 6, a 31-3 blowout by a Colts team that had just one win prior. Davis Mills passed for 243 yards but two INTs. A Houston defense that had been OK got gashed by Jonathan Taylor, too. Its own run game ranks last in yards per play, but perhaps that can be rectified vs. a Cardinals defense that ranks 31st in yards allowed per rush.

The unbeaten Cardinals were underdogs at Cleveland on Sunday, so how did they react? By pounding the Browns, 37-14. Kyler Murray strengthen his NFL MVP case with four TDs and no INTs while the defense forced three Baker Mayfield turnovers. The Cardinals are one of two teams to rank in the top 10 in both passing and rushing (Chiefs).

Take a look at Texans vs Cardinals odds, injury report, betting lines and more.

Chicago Bears at Tampa Bay Buccaneers (-12), 4:25 p.m. ET

Chicago’s defense allowed under 10 ppg the last three weeks before Aaron Rodgers accounted for three TDs in a 24-14 Packers win at Soldier Field in Week 6. The offense moved the ball but struggled to score. A Justin Fields INT in the end zone didn’t help, but despite missing their top two RBs, the Bears rushed for 140 yards and 5.4 yards per carry.

Only once has the Bears defense allowed more than 260 yards of passing (Week 1 vs. Matthew Stafford and the Rams), but Tom Brady and the Buccaneers have finished lower than 295 yards once, and that was 262 in a 45-17 win. The Bucs found a way at Philadelphia last week thanks to a defense that held the Eagles to just 213 total yards. Chicago’s run-first offense likely doesn’t scare Tampa with its top-ranked run defense.

Take a look at Bears vs Buccaneers odds, injury report, betting lines and more.

Indianapolis Colts at San Francisco 49ers (-4.5), 8:20 p.m. ET

One week after getting outscored 22-3 in the fourth quarter and overtime in a loss to the Ravens, the Colts kept the pressure throughout a 31-3 rout of the Texans in Week 6. Jonathan Taylor had his best game as a pro, with 14 carries for 145 yards and two TDs. The game before that, Carson Wentz passed for 402 yards. The team ranks in the upper-half in both total offense and defense despite the 2-4 record.

The bye week couldn’t have come at a better time for the Niners, who after a 2-0 start had dropped three straight, all by a TD or less. Questions remains on offense, namely who the best QB is for the team and who can run the ball most effective. But a defense that ranks seventh can carry additional load.

Take a look at Colts vs 49ers odds, injury report, betting lines and more.


Two Risk-Free Bets up to $2,000 - Promo Code: BOOKIESB

Bet Now

Monday, Oct. 25

New Orleans Saints (-4.5) at Seattle Seahawks, 8:15 p.m. ET

The Saints alternated wins and losses through the first five weeks before a bye to reassess situations. One that doesn’t need addressing: Alvin Kamara, who leads the team in rushing and in pass receptions. New Orleans’ pass defense is top-tier as well. Jameis Winston has an impressive 12 TDs to just three INTs but ranks 31st in yards.

Geno Smith was serviceable in his first start as replacement for Russell Wilson, but a critical turnover in OT and a lack of big plays (6.5 yards per attempt) cost them in a 23-20 loss at Pittsburgh. Seattle’s defense made a big leap, however, holding Ben Roethlisberger to 229 yards, this after allowing over 300 per game through the air.

Take a look at Saints vs Seahawks odds, injury report, betting lines and more.

Teams on Bye Week: Buffalo Bills, Dallas Cowboys, Jacksonville Jaguars, Los Angeles Chargers, Minnesota Vikings, Pittsburgh Steelers

NFL Week 7 Odds Biggest Favorites

We have three home teams favored by double digits in NFL Week 7 spreads.

Cardinals (-17.5) over TexansArizona should roll to a 7-0 start vs awful Texans
Rams (-14.5) over LionsDetroit looks to get steamrolled in LA
Buccaneers (-12) over BearsChicago heads to Tampa for a late Sunday start
Packers (-7.5) over Washington Rodgers has Green Bay rolling; lined move 3.5 points toward GB on Sunday

About the Author

Adam Thompson for
Adam Thompson
NFL writer and expert Adam Thompson joined in 2019 after a successful run as senior handicapper for SportsLine and