If Oregon had its way, maybe the nonconference season would never end. After an impressive showing that included two wins over top-25 opponents, the Ducks get a presumably soft landing to start Pac-12 play when they host Arizona on Saturday at 7:30 p.m. local time (10:30 p.m. ET).

As seen in our college football odds table below, the Ducks are favored by more than four touchdowns against the Wildcats, who drag a 15-game losing streak into this matchup. Something to keep in mind if heading to Arizona sports betting sites for a wager.

Oregon is the conference’s greatest hope for a College Football Playoff berth, and a loss to Arizona would change that landscape significantly. Check out our college football picks for this matchup in the article below.

Odds are current as of publication. Betting sites may indicate odds changes closer to kickoff.

5 Keys To Arizona vs Oregon

Brown ‘OK’ after injury: Oregon quarterback Anthony Brown didn’t play in the second half last week, but coach Mario Cristobal said he’s “OK” and that they “expect him to be healthy for the week.” Freshman Ty Thompson did well in Brown’s place, but fifth-year senior Brown is crucial to this offense.

Slow starts: If you like Oregon, you’ve probably preferred watching them in the second half as opposed to the first half this season. They started slow against No. 25 Fresno State in Week 1 (leading by eight at the half, then trailing in the third quarter) and against FCS Stony Brook last week (leading by 10 at half). If you find a juicy halftime point spread, consider fading the Ducks.

Behind enemy lines: Not a lot of positives stick out for Arizona, but its defense has done a great job pushing past the line of scrimmage. The Wildcats have 21 tackles for loss through three games, which is tied for second in the Pac-12.

QB conundrum: There are three candidates for Arizona’s starting quarterback role, and that’s not what you want entering the fourth week of the season. Arizona coach Jedd Fisch said he’s taking the next couple of days in practice to evaluate the trio of Will Plummer, Gunner Cruz and Jordan McCloud, who’ve combined for five touchdowns and four interceptions.

Still seeking first ‘W’: Fisch has yet to find the win column during his first year at Arizona. The Wildcats’ losing streak dates back even further, though, thanks to an 0-5 season last year. Arizona last won a football game on Oct. 5, 2019.

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Arizona vs. Oregon Weather Forecast

Expect a cool, clear evening in Eugene, Oregon on Saturday, with low-60s temperatures and a 10 percent chance of rain. Wind will be a non-factor.

Arizona vs Oregon Moneyline

Look, Arizona hasn’t won a game in almost two full years, and the sportsbooks are well aware of that. So there’s no reason to be shocked by the state of Oregon’s moneyline odds (-5000). On their own, they won’t net you very much.

If you’re going to pick anyone on the moneyline, though, it has to be Oregon. Arizona is nothing more than a lottery ticket.

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Arizona vs Oregon Point Spread

Oregon is 1-2 in college football betting against the spread, but that includes missing a 42-point cover by one point against FCS Stony Brook and beating an underrated Fresno State squad by seven as 17.5-point chalk (Fresno State is 3-1 and nationally ranked).

Arizona is also 1-2 ATS, but its two losses came in straight-up fashion as favorites. That includes last week’s 21-19 loss to FCS Northern Arizona as 26-point chalk. Ouch. We like the Ducks, favored by 28.5 points on betting apps, to cover this one. You can get Oregon -28.5 at BetMGM .

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Arizona vs Oregon Totals

The status of Oregon pass rusher Kayvon Thibodeaux, who is day-to-day but hasn’t played since Week 1, could change the equation here. Still, a 58.5-point total is a fairly high bar to climb, and one of these teams doesn’t know who its real quarterback is.

These teams have seen the under hit in four of their combined six games, and we think they’re headed that way again Saturday. You can get Under 58.5 at -108 with FanDuel .

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