NFL Week 18 Odds & Lines: Complete Spreads, Moneylines & Totals

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All 16 matchups for the final week of the regular season – the first Week 18 of NFL history – features divisional matchups. A few of those showdowns features playoff-bound teams against squads trying to scrap their way into the postseason.

It brings to question the motivation of those who may prefer to ensure playoff health over a higher overall draft pick. Could that benefit those who are in must-win mode? It makes setting NFL Week 18 odds – and NFL betting this week – so challenging.

Those looking for a motivational boost can possibly look at the Indianapolis Colts, who are in the playoffs with a victory. They are at the Jacksonville Jaguars, who can secure the No. 1 overall pick in the 2022 NFL Draft with a loss.

It’s also a win-and-in scenario for San Francisco 49ers, who are at a Los Angeles Rams team that needs a win to clinch the NFC West. There will be no question of motivation when the Las Vegas Raiders host the Los Angeles Chargers. The winner gets into the postseason; the loser is likely left out.

It makes for a wild inaugural Week 18 for making NFL picks. Let’s dive into our analysis of all the matchups and NFL Week 18 lines.

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Saturday, Jan. 8

Kansas City Chiefs at Denver Broncos, 4:25 p.m. ET

Take a look at Chiefs vs Broncos odds, injury report, betting lines and more.

Kansas City had won eight in a row and allowed just 13 ppg the last six weeks before getting blitzed by Joe Burrow and the Bengals in Week 17. Facing Denver has been a favorable matchup regardless of the personnel. The Chiefs have beaten the Broncos 12 consecutive times, with four of the last five by at least 13 points. Patrick Mahomes is a perfect 8-0 over his career, though he has only 10 TDs. The line shifted a touchdown Sunday night toward the Chiefs to a whopping -10.

The Broncos have allowed fewer points than any team, and yet even that isn’t good enough with the horrible offense on the other end. Denver is 0-7 when allowing 18 or more points. It hasn’t held KC to 17 or fewer since 2014. QB Teddy Bridgewater’s four best games this season came in the opening six weeks. It’s unknown if he’ll play after missing the last two games (concussion).

Dallas Cowboys at Philadelphia Eagles, 8:15 p.m. ET

Take a look at Cowboys vs Eagles odds, injury report, betting lines and more.

The Dallas offense has rediscoverd its groove, thanks to the improvements on the ground game. Ezekiel Elliott and Tony Pollard have sparked a Cowboys run offense that is averaging 147.2 ypg in Dallas’ 11 wins, compared to 65.8 in the five losses. The Cowboys have beaten the rival Eagles by 20 points in each of the last two meetings.

Sure, Philly was trounced last time out vs. Dallas, but that was back in Week 3. Philly RBs had just three carries as they put the game on the arm of Jalen Hurts – and that didn’t work. But now they’ve won seven of nine and own the NFL’s No. 1 rushing attack, gaining at least 176 yards in seven of nine. Dallas ranks 12th vs. the run.


Sunday, Jan. 9

Green Bay Packers at Detroit Lions, 1 p.m. ET

Take a look at Packers vs Lions odds, injury report, betting lines and more.

The Packers have already locked up the No. 1 seed in the NFC and with it a first-round bye and homefield advantage, so don’t expect many of their regulars, including (and especially) Aaron Rodgers. Green Bay has won 19 of 20 at home and handled the Lions in five straight, through the last two in Detroit have been by a TD or less.

After starting the year 0-10-1, the Lions have played better down the stretch, winning two of four before allowing 51 points to the Seahawks in Week 17. Detroit actually outgained Green Bay in its 35-17 loss in Week 2 but lost the turnover battle. The Lions are 2-1 when Jared Goff tosses three TDs. Green Bay has allowed the fifth-most TD passes.

Washington Football Team at New York Giants, 1 p.m. ET

Take a look at Washington at Giants odds, injury report, betting lines and more.

Washington held a nine-point lead over Philadelphia in Week 17 but didn’t score in the second half, ending its postseason hopes. The offense is predicated on the success of RB Antonio Gibson. The team is winless when he doesn’t at least get 60 rush yards, but the defense needs to step up, too, allowed 449 ypg the last three weeks, this after allowing 292 ypg the previous seven games.

The Giants offense, however, has bottomed out since QB Daniel Jones was lost for the year. In the last six games, New York has surpassed 13 points just once and averaged 256 ypg. Last week vs. the Bears, Mike Glennon and the pass game registered minus-10 net pass yards. Perhaps this is the perfect opponent to end on. Washington’s defense has had major issues lately, and New York achieved its season-best 29 points vs. WFT back in Week 2.

Chicago Bears at Minnesota Vikings, 1 p.m. ET

Take a look at Bears vs Vikings odds, injury report, betting lines and more.

Matt Nagy is likely to be let go after this season as Chicago’s head coach, but the team has won two straight. It’s mostly thanks to a pass defense that has limited opponents to under 200 yards in six of the last seven games, including a ridiculous -10 net pass effort by the Giants in Week 17. The road team has won the last four in this series.

Minnesota 4-1 when RB Dalvin Cook gets into the end zone and 1-6 when he doesn’t – the one win in that instance was vs. Chicago. He averages only 3.5 ypc vs. Chicago lifetime. Kirk Cousins had just 87 pass yards in their Week 15 matchup. Again, Minnesota still won, and Cousins has passed for 260-plus in five of the other seven games against the Bears.

Tennessee Titans at Houston Texans, 1 p.m. ET

Take a look at Titans vs Texans odds, injury report, betting lines and more.

Over the last seven games, the Titans have three games with 4-5 turnovers, with none in any of the other four. Needless to say, they’re 4-3 in that span. Despite offensive inconsistencies, thanks in part to injuries and protocols, the Titans are going to the playoffs and are currently the No. 1 seed in the AFC. The defense ranks No. 2 vs. the run but a susceptible No. 26 vs. the pass.

When these teams played in Week 11, the Texans won the turnover battle 5-0 and the game 22-13. Houston ranks bottom-3 in the NFL in rushing and passing offense, but Davis Mills has shot some life into the unit. After averaging 10.5 ppg his first nine starts, Houston has put up 78 points the last three games.

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Pittsburgh Steelers at Baltimore Ravens, 1 p.m. ET

Take a look at Ravens vs Steelers odds, injury report, betting lines and more.

It could be Ben Roethlisberger’s final game, and it’s against the AFC North team he’s had the most trouble with, though he and the Steelers are riding a three-game win streak vs. Baltimore. And he’s still been decent: 16-10 record, 42 TDs and 24 INTs. Baltimore ranks No. 1 vs. the run and dead-last vs. the pass, so Big Ben could go out on a very high note here. If the chips fall, the Steelers could still get into the playoffs.

Five opponents have passed for 340-plus yards and six for 225 or less vs. the Ravens. Roethlisberger’s season-high is 318 and half his games he’s been limited to 236 or less. Baltimore is 5-1 when the opposing QB goes for under 236. The Ravens need to win here and get some help to advance to the postseason for a fourth consecutive year. QB Lamar Jackson (ankle) is expected back after missing most of the last four games, all losses.

Indianapolis Colts at Jacksonville Jaguars, 1 p.m. ET

Take a look at Colts vs Jaguars odds, injury report, betting lines and more.

After Tennessee’s Derrick Henry was lost for the season, Jonathan Taylor emerged as the NFL’s top running back. And Indy’s success emerged with that realization. The Colts are 9-1 when Taylor rushes for over 85 years and 0-6 when he doesn’t. Jacksonville is 0-11 when the opponent gains 85 on the ground.

Jacksonville has actually won the last six meetings in Florida and outgained the Colts in a 23-17 loss in Indy in Week 10. But the defense has forced just seven turnovers, and three of those were in the same game (a win vs. the Bills). The Jaguars also lead the NFL in turnovers. Based on Week 17’s 50-10 loss to the Patriots, they’re just playing out the season.

Top betting sites forecast a huge Colts victory and moved the line six points to -14.5 on Sunday night, including at Caesars Sportsbook, where the Caesars Sportsbook promo code gives new bettors a first-bet match of up to $1,001.

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Cincinnati Bengals at Cleveland Browns, 1 p.m. ET

Take a look at Browns vs Bengals odds, injury report, betting lines and more.

Cincy has clinched its first AFC North title since 2015 led by the arm of Joe Burrow. Just the last two weeks, Burrow has thrown for 971 yards and eight TDs. The Bengals rank seventh in scoring, their best mark since that past playoff year, and the top-five run defense is just what the doctor ordered against the run-first Browns.

Cleveland is out of the playoff race but has had success vs. their in-state rival, winners of six of the last seven including a 41-16 rout in Cincy on Nov. 7. The last four games have each totaled at least 56 points, so offenses will need to keep up with one another here.

Carolina Panthers at Tampa Bay Buccaneers, 4:25 p.m. ET

Take a look at Panthers vs Buccaneers odds, injury report, betting lines and more.

Sam Darnold remains the starter, but the second half of the year has been very unkind. Darnold has averaged under 160 ypg the last six outings, with two TDs and nine INTs. He has no TDs his last five games, including a 32-6 drubbing by these Bucs just two weeks ago. Carolina does still own the NFL’s second-ranked pass defense, a good trait vs. Tom Brady.

Tampa Bay’s offense must be contained if Carolina is to compete. The Buccaneers have won eight straight when scoring 30 or more points and dropped three of four when they don’t hit that level (they scored 28 in that lone exception). They’ve scored 30-plus in every matchup with the Panthers with Tom Brady under center.

The best sportsbooks in the US moved the line a full touchdown from -16.5 to -9.5 on Sunday, including at BetMGM, where you can get a $1000 risk-free bet using the BetMGM bonus code.

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New England Patriots at Miami Dolphins, 4:25 p.m. ET

Take a look at Patriots vs Dolphins odds, injury report, betting lines and more.

New England just beat Jacksonville by 40 and now gets a Miami team with both playoff positioning and revenge motivation in play. The Dolphins won a Week 1 matchup 17-16, thanks in large part to a fumble inside the 10 that ended the game. The Pats outgained the Dolphins by nearly 150 yards and had the ball for 13 more minutes. The matchups are there for New England, whose No. 3-ranked pass defense goes against a team that has far more production passing than rushing. That’s why the Patriots are solid favorites on the road in Week 18 odds.

Miami’s seven-game win streak – and playoff hopes – both ended emphatically in 34-3 loss to the Titans in Week 17. Amazingly, only one opponent passed for over 210 yards during the seven-game victory stretch. Mac Jones went for 281 against them in Week 1.

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New Orleans Saints at Atlanta Falcons, 4:25 p.m. ET

Take a look at Saints vs Falcons odds, injury report, betting lines and more.

The Saints are still in the playoff mix but need help going into the season finale. The team has scored 30 total points the last three weeks but 21-plus points in six of the last seven games vs. the Falcons. Alvin Kamara is on pace to have 30 fewer receptions than any other season and is averaging a career low in rush yards per carry. He had a solid five catches for 68 yards and a TD vs. Carolina in Week 17. Atlanta has allowed the eighth-most RB receptions.

Atlanta is out of the postseason conversation, but its 7-9 record isn’t bad considering the team ranks bottom-10 in both total offense and total defense. Matt Ryan went off for 332 yards and two TDs in the first meeting between these teams, a 27-25 Atlanta win. He’s averaged a huge 296 ypg in 26 career matchups with the Saints.

New York Jets at Buffalo Bills, 4:25 p.m. ET

Take a look at Jets vs Bills odds, injury report, betting lines and more.

The Jets are still learning how to win, but the last two weeks we’ve seen a glimpse. They beat the downtrodden Jaguars two weeks ago thanks to 273 rush yards, then in Week 17 had the champion Buccaneers on the ropes in a 28-24 loss in the closing seconds. They’re 2-0 on their two biggest rushing days and 2-11 in all the others. Buffalo has the NFL’s top-ranked pass defense but is just 17th vs. the run.

Of course, the last time these teams played, the Bills scored 45 points. Buffalo is 10-2 when it scores a modest 20-plus points. The Jets have allowed under 20 points twice, to the Panthers and Texans, the 28th- and 32nd-ranked offenses. Buffalo ranks sixth. Against top-11 offenses, the Jets have allowed nearly 40 ppg.

A number of New York betting sites are now live following the launch of online betting in the Empire State on Saturday. New Yorkers can score great deals, like up to $3,300 in free bets at Caesars Sportsbook New York.

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San Francisco 49ers at Los Angeles Rams, 4:25 p.m. ET

Take a look at 49ers vs Rams odds, injury report, betting lines and more.

San Francisco has won six of eight and controls its own destiny for a playoff berth heading into the final week. The Niners are averaging 162.5 rushing yards per game in the five wins compared to just 77 in the two losses. The Rams aren’t easy to run on, but the Niners have had their number, winning the last five matchups, including a 31-10 beatdown just one month ago.

The Rams defense has been stellar at home, allowing under 202 yards per game in the last three games there, compared to close to 400 ypg the last four on the road. The offense has regained its momentum, too, scoring 30-plus three times in this five-game win streak. Cooper Kupp, in line to win the WR Triple Crown, had 11 receptions for 122 yards vs. the 49ers in November.

Seattle Seahawks at Arizona Cardinals, 4:25 p.m. ET

Take a look at Seahawks vs Cardinals odds, injury report, betting lines and more.

The Seahawks’ nine-year run of winning records ended emphatically, finishing last in their division for the first time in 21 years. Russell Wilson’s QBR was by far the lowest of his career. That said, he has been successful vs. the Cardinals, with 29 TDs and eight INTs, and he’s coming off one of his best games, a four-TD performance in a 51-29 rout of the Lions. Oddly, Seattle’s defense ranks 31st in yards allowed but only seventh in points allowed.

The Cardinals snapped a three-game losing streak by winning at Dallas in Week 17, earning their first playoff berth since 2015, great timing for hometown fans with Arizona sports betting legal. An offense that scored 31-plus in six of its first seven games has still managed 23 or less in five of seven. QB Kyler Murray didn’t face the Seahawks in Week 11, a 23-13 Arizona win, but he passed for 360 and 269 yards vs. them last year with five TDs.

Los Angeles Chargers at Las Vegas Raiders, 8:20 p.m. ET

Take a look at Chargers vs Raiders odds, injury report, betting lines and more.

The Chargers shut down Derek Carr and the Raiders in a 28-14 victory in Week 4. Carr has just 138 ypg vs. L.A. over the last three matchups. The Chargers rank No. 12 vs. the pass, but on the road, they’re giving up just 191.8 ypg, the third lowest.

The Raiders climbed back into the playoff conversation on the backs of their defense, which has limited four of the last five opponents to 20 points or less. Grinding the ball out with Josh Jacobs is working; Vegas is 5-1 when he gets 15-plus carries. Last-second win over Colts in Week 17 gives them tiebreaker over Indy.

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Opening NFL Week 18 Odds vs Current Spreads

How have the NFL odds for this week changed on betting apps since they were released? Here are the opening and current NFL Week 18 betting lines via DraftKings. Be sure to check out the DraftKings promo code for some great new customer offers.

Game matchupOpening SpreadCurrent Spread
Carolina Panthers at Tampa Bay BuccaneersBuccaneers -16.5Buccaneers -9
Washington Football Team at New York GiantsWashington -4Washington -6.5
New Orleans Saints at Atlanta FalconsSaints -3.5Saints -3.5
Dallas Cowboys at Philadelphia EaglesCowboys -3.5Cowboys -4
Indianapolis Colts at Jacksonville JaguarsColts -8.5Colts -14.5
Cincinnati Bengals at Cleveland BrownsBrowns -1.5Browns -5
Tennessee Titans at Houston TexansTitans -10Titans -10.5
Pittsburgh Steelers at Baltimore RavensRavens -6.5Ravens -3.5
Green Bay Packers at Detroit LionsPackers -11Packers -3.5
Chicago Bears at Minnesota VikingsVikings -4Vikings -4
New York Jets at Buffalo BillsBills -17Bills -16.5
New England Patriots at Miami DolphinsPatriots -2.5Patriots -6
Seattle Seahawks at Arizona CardinalsCardinals -5Cardinals -5.5
Los Angeles Chargers at Las Vegas RaidersChargers -2.5Chargers -3
San Francisco 49ers at Los Angeles RamsRams -6.5Rams -3.5
Kansas City Chiefs at Denver BroncosChiefs -3Chiefs -10.5
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