The AFC rivalry between Patrick Mahomes and Lamar Jackson resumes on Sunday Night Football when the Baltimore Ravens host the Kansas City Chiefs. One of these teams has finished with the best record in the AFC three years running.

Betting sites and most betting apps have Kansas City at -3 in the latest Chiefs vs. Ravens NFL spreads range. It is the marquee matchup of Week 2 of the 2021 NFL season.

RELATED: NFL Week 2 Odds & Betting Lines and be sure to check out more Ravens vs. Chiefs odds.

Chiefs vs. Ravens Key Matchups

Lamar Jackson vs. Chiefs Pass Defense: In three games, Jackson has passed for 147, 267 and 97 yards. KC was torched by Baker Mayfield in Week 1 for 321 yards, but no TDs and a game-clinching INT in the end.

Sammy Watkins vs. Old Team: Watkins played three seasons with Mahomes and the Chiefs, but 2020 was his least-productive (37 catches, 421 yards, two TDs, all lows). In his first start for Baltimore, Watkins had a team-high eight targets, at 96 yards on four receptions, showcasing an immediate bond with Jackson. Watkins should be extra motivated in this spot against his old team.

CEH vs. Ravens Front 7: Chiefs RB Clyde Edwards-Helaire managed only 43 yards on 14 carries (3.1 per carry) in Week 1. He’ll look to improve upon that, or at least closer to his 4.4 average, against a Ravens defense that allowed 4.3 per rush last year.

RELATED: NFL Week 2 Odds & Betting Lines For All 16 Matchups

5 Key Chiefs vs. Ravens Stats

0: Career yards gained by Ravens RB Ty’Son Williams before gaining 65 yards on nine carries and a TD in Baltimore’s 33-27 OT loss to the Raiders. Latavius Murray led RBs with 10 carries, but for just 28 yards.

45: Wins by the Chiefs over the last three seasons and after Week 1, compared to just 12 defeats. No team has won more than KC in that span.

58.5: The QB rating for Jackson in three games against the Chiefs, all losses. He has just three TDs in those games and a 52.6% completion percentage.

99: Career wins in Kansas City for head coach Andy Reid. He compiled 130 wins with the Eagles; no coach has won 100 games with two franchises.

457: Yards allowed in Week 1 by the Chiefs, to Baker Mayfield (304 through the air) and the Browns run game (153), the most since the 490 given up in Week 5 of 2020 against the Raiders. They’d held seven of their previous eight regular season opponents to under 400.

Chiefs vs. Ravens Player Props To Consider

Lamar Jackson, Under 220.5 Pass Yards

Odds: -115 at DraftKings

Jackson has not fared well vs. the Chiefs, averaging a scant 170 ypg through the air in three career meetings. Certainly KC’s pass defense isn’t good, but that’s a big number to ask for a QB that can always take off. Jackson eclipsed 221 pass yards just three times in 15 games last year.

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Patrick Mahomes, Over 317.5 Pass Yards

Odds: -110 at DraftKings

Mahomes passed for 337 yards against a Browns defense that I rank top 3 in the NFL. The Ravens D got steamrolled by Derek Carr to the tune of 435 pass yards. Mahomes, in three games vs. Baltimore, has averaged 379 ypg.

Patrick Mahomes, Under 0.5 Interceptions

Odds: -195 at DraftKings

Patrick Mahomes has never thrown an interception in the month of September. Ever. And he has 35 TDs, too. The man comes into seasons ready to play. He’s tossed one INT vs. the Ravens in three games.

Mecole Hardman, Over 36.5 Receiving Yards

Odds: -115 at PointsBet

Hardman had a disappointing debut as the new starter for the Chiefs, catching just three passes for 19 yards. More is expected from the No. 3 option in the KC pass attack.

Both Teams Score In Every Quarter

Odds: +400 at FOX Bet

Each team has an offense that can move the ball, and each has a kicker that doesn’t need to get too close for a chance. The defenses ranked 31st and 32nd in yards allowed in Week 1. Points will be scored.

Chiefs vs. Ravens Weather Forecast

Clear skies and temperatures in the 60s and 70s are expected for Sunday night in Baltimore. That’s following a sunny day in the 80s, meaning the field and conditions should be ideal for this marquee showdown.

Chiefs vs. Ravens Moneyline

When it comes to NFL betting on the moneyline in this rivalry, Mahomes has bested Jackson in all three career matchups. Last season it was a 34-20 handling in prime time; the other two matchups came down to one score.

For Sunday Night, the Chiefs are around -190 on the moneyline, the Ravens are +135. Certainly the Chiefs have had the Ravens’ number recently. More concerning for Baltimore was the beatdown put upon its defense by Derek Carr and the Raiders in Week 1.

Carr passed for 435 yards, the most of any QB in Week 1. That, coupled with Mahomes’ typical mastery and KC’s penchant for getting it done vs. Baltimore, makes KC an enticing ML pick. You can get the Chiefs -200 at BetMGM .

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Chiefs vs. Ravens Point Spread

The Chiefs are favored by a single field goal, but the game is on the road. Kansas City was favored in all eight road games last season, covering just three times. Baltimore was only 5-3 ATS at home in 2020, but its average margin of home games was +11.3, best in the NFL.

The last season the Ravens were underdogs at home, and they covered those two games by an average of 20 points.

Kansas City’s defense struggled with Cleveland’s run game in Week 1. Baltimore’s RBs aren’t as good as Cleveland’s, but Jackson can wreck havoc with his feet. KC needed a furious rally to beat the Browns.

It won’t be as likely against a Ravens defense that ranked No. 1 in fewest points allowed in 2020. Baltimore has more questions than answers following its Week 1 loss at Las Vegas. Let’s see if we can get value away from the three-point spread later in the week.

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Chiefs vs. Ravens Totals

NFL sportsbooks have posted the relatively high Over/Under of 55.5 points for Sunday Night Football. That’s the highest total of Week 2, just in front of the 55 posted for Cowboys vs. Chargers.

The three Mahomes vs. Jackson matchups have averaged 55.3 ppg. So does either side make sense when forming your own NFL picks for Week 2?

Judging from Week 1, the Over looks enticing. The Chiefs played the Browns to a 33-29 nail-biter, while the Ravens and Raiders played a wild 33-27 overtime showdown on Monday. Each totaled 60-plus points. Offenses should have the edge in this one, too. The Over looks better than the Under. You can get Over 54.5 at -115 with DraftKings .

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