NFC rivals licking their wounds from Week 1 losses look to rebound on Monday Night Football when Aaron Rodgers and the Green Bay Packers host Jared Goff and the Detroit Lions at Lambeau Field. The Packers were routed 38-3 by the New Orleans Saints, while the Lions trailed the San Francisco 49ers 41-17 in the fourth quarter before a late surge made it 41-33.

Betting sites and betting apps have installed Green Bay as hefty 10.5-point favorites, with an Over/Under of 48 points in the latest Lions vs. Packers odds.

But is this among the NFL spreads to attack or avoid?

Lions vs. Packers Key Matchups

Aaron Rodgers vs. Himself: After a drama-filled offseason, Rodgers had one of the worst efforts of his Hall of Fame career vs. the Saints. The Lions don’t have the personnel to stop No. 12 on his game. The question is, will his head and heart allow it?

Jared Goff vs. Packers Pass D: Goff threw for 338 yards and three TDs in his Lions debut at QB, but nearly all of it came in the second half of a furious rally. Green Bay allowed five TDs to Jameis Winston but only 155 total yards.

D’Andre Swift vs. Packers Run D: Take away a 16-yard scamper and Swift had 10 carries for 23 yards otherwise. He averaged 4.6 ypc last year, however, and the Packers allowed 4.7 yards per rush at home last year, sixth-highest.

RELATED: NFL Week 2 Odds & Betting Lines For All 16 Matchups

5 Key Lions vs. Packers Stats

.500: The win percentage by the Lions at Lambeau Field over the last six seasons. Prior to that run, Detroit had dropped 24 straight games in Wisconsin.

4: Missed field goals for Mason Crosby since October 2018, when he missed four in one game vs. the Lions. That’s a span of 41 games.

30: Targets for RBs D’Andre Swift and Jamaal Williams and TE T.J. Hockenson from Goff in Week 1. Starting receivers Kalif Raymond and Tyrell Williams combined for seven.

43: Yards rushing by the Packers vs. the Saints, including just nine yards on five carries from lead RB Aaron Jones. Detroit’s 5.0 yards allowed per carry on the road in 2020 was fourth worst.

120.25: The average QB rating for Aaron Rodgers in the week following a game in which his rating was under 60. It’s only happened twice since 2015 prior to the Packers’ Week 1 loss to the Saints. His QB Rating last Sunday was 36.8. Something for Michigan sports betting fans to keep in mind.

Lions vs. Packers Player Props To Consider

Aaron Rodgers, Over 2.5 TDs

Odds: +120 at DraftKings

Rodgers has feasted on the Lions over his NFL career. Through 22 games, the Packers QB has tossed 46 TDs in 22 games. Rodgers was embarrassed in Week 1 vs. the Saints, and he knows people are saying he didn’t prep enough in the offseason. Here’s his shot to put doubters in their place – a personal hobby of his.

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Jared Goff, Over 35.5 Attempts

Odds: -115 at DraftKings

Goff attempted 57 passes in Week 1, way over this posted total. Obviously throwing it nearly 60 times isn’t a recipe for success, it’s an attempted elixir after getting in a hole early. Would anyone be surprised if we see a similar scenario play out at Lambeau on Monday night?

Mason Crosby, Over 2.5 Extra Points

Odds: -175 at DraftKings

Clearly I’m banking on the Packers scoring in bunches against last year’s worst defense. The team allowed a Week 1-most 41 points and that was with the 49ers taking the pedal off the gas for an entire half. Crosby has missed 16 extra points in 663 tries.

T.J. Hockenson, Over 48.5 Receiving Yards

Odds: -115 at DraftKings

Hockenson was the favored target of Goff in the season opener, hauling in eight of 11 targets for 97 yards and one TD. He should be a first look often again on Monday. Green Bay was throttled by New Orleans tight ends, to the tune of six receptions for 40 yards and two TDs.

Packers Score Every Quarter And Win

Odds: -105 at FOX Bet

Certainly the Lions will score; they put up 33 points in Week 1, albeit most of that was against a Niners team that had mentally packed it up with a huge lead. We also know, however, the Packers won’t be held to three points. Detroit had the worst defense in the NFL last year in most categories, and will be missing a couple of key players this week.

Lions vs. Packers Weather Forecast

It’s unseasonably warm in northeastern Wisconsin. Monday’s high is slated to be in the upper 80s, with temps for game-time around 70 degrees. With clear skies and little wind, it is ideal weather for Monday Night Football at Lambeau Field.

Lions vs. Packers Moneyline

The Packers are a hefty -575 on the moneyline, meaning it would take a $575 wager to win $100 in profit. Conversely, the underdog Lions are +410 (a $100 winning bet means $410 in profit). It’s one of the bigger moneyline spreads at sportsbooks for NFL Week 2.

And it’s too big to bet on for the Packers, especially after their Week 1 drubbing at the hands of Jameis Winston and the Saints. As for the Lions, they’re also a wait-and-see team.

Will it be the Detroit team that fell behind huge to the Niners in Week 1, or the one that furiously rallied in the fourth quarter? Detroit hasn’t won since Oct. 27, 2020, a span of 10 losses straight. It’s a stay-away line.

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Lions vs. Packers Point Spread

The Packers are -10.5 on the point spread, which means sportsbooks are daring you to back Detroit in your weekly NFL betting lineup. The “hook” makes a Lions bet tempting.

While the Lions have dropped 10 in a row, only one of those defeats was by more than 10 points. There are, of course, stark differences between the Lions team of last year and this year, notably at QB – Jared Goff instead of Matthew Stafford – and a defense that is hopefully better than the last-ranked unit of a year ago.

As for the Packers, it’s more of a mystery as to which team shows up. The line isn’t enticing for Green Bay backers, but if you’re seeking to add a Monday bet to your NFL picks of the week, Lions +10.5 might be it. You can make the bet at BetMGM .

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Lions vs. Packers Totals

The Over/Under for Monday Night Football sits at 48. That is higher than the total for both matchups last year, which featured an MVP Rodgers guiding the top-scoring Pack, and a high-volume Stafford at QB. Those games finished at 45 and 43 points.

It’s tough to project which way the wind blows at Lambeau Field on Monday. Most assume Rodgers finds his form after a dreadful outing, overshadowed by a tumultuous offseason. The Lions scored 33 points in Week 1 and allowed 41. The Over looks better than the Under. You can make the bet at DraftKings .

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