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Biggest College Football Point Spreads and How to Bet Them

David Caraviello for Bookies.com

David Caraviello  | 4 mins

Biggest College Football Point Spreads and How to Bet Them

Every week you'll find monster college football betting point spreads, making those points (and some of those huge moneylines) very tempting, too. Here's how you should approach them.

And check out our Bookies.com expert college football picks to get ready for the weekend.

Largest Week 14 College Football Point Spreads

Game Underdog Moneyline
Penn State (-38.5) vs. RutgersN/A
Buffalo (-29.5) vs. Bowling Green N/A
Temple (-28.5) vs. Connecticut N/A
Georgia (-28) at Georgia Tech N/A
Utah (-28) vs. Colorado N/A
UCF (-25) vs. South Florida N/A
Clemson (-24.5) at South Carolina N/A
Michigan State (-21) vs. Maryland +1000
Tennessee (-21) vs. Vanderbilt +1075
Louisiana-Lafayette (-21)
vs. Louisiana-Monroe

A Final Stand For Rutgers At +38.5? Not Likely

It’s the last week of college football’s regular season — which means we can’t avoid talking about Rutgers any longer.

The Scarlet Knights have been regulars on our lists of biggest point spreads of each weekend. Five times previously they’ve been underdogs of 21 points or greater, and the sixth time arrives Saturday, when Rutgers is a 38.5-point home underdog against Penn State.

That’s the biggest line of the weekend not involving an FCS opponent, and the second-biggest spread Rutgers has faced this season — behind the mammoth 52-point line against Ohio State.

And yet, the Scarlet Knights covered that day against the Buckeyes, who eased off the throttle and won by 35. It was one of just three Rutgers covers all season, the others coming in the program’s two wins over Massachusetts and Liberty.

CHECK OUT: College Football Coaching Hot Seat & Betting Tracker Week 14

So, what to make of Penn State giving 38.5? To say the least, these are lean times for Rutgers, which suffers from waning attendance, fired coach Chris Ash in midseason, and reportedly couldn’t reach a deal with Greg Schiano to return to the program he once had at a respectable level.

The Scarlet Knights lost by 52 to Michigan, 42 to Maryland, and 35 to Indiana and Minnesota, and Penn State is better than any of those teams.

So yeah, it all shapes up as one last ugly outing for New Jersey’s state university. The line is a big one, but the Nittany Lions are the only sensible bet.

Can Clemson cover 24.5 at South Carolina?

Biggest College Football Point Spreads and How to Bet Them 1

Clemson is favored by 24.5 points against rival South Carolina on Saturday in Columbia, a line that by itself indicates how far apart the two programs are. But it’s even worse than that: the point spread is the largest ever for a road team in the history of the series, according to Matt Smith of the Palmetto State’s “Sports Talk” radio program.

It’s easy to see why. In six games since the scare at North Carolina — when the Tar Heels failed to convert a two-point conversion that would have upset the Tigers — Clemson is winning by an average margin of 42.8 points per game. The Tigers beat Louisville by 35, Florida State by 31, Wake Forest by 49 — and those are better teams than South Carolina, whose upset at Georgia stands as a great aberration in a lost Gamecocks’ season.

If anything, South Carolina has gotten worse as the season has worn on, with the Gamecocks’ offensive struggles becoming more magnified each week. Another big line, and another compelling case to go with the favorite.

Can Georgia Tech cover +28 against Georgia?

Biggest College Football Point Spreads and How to Bet Them 2

Even with Tua Tagovailoa watching from the sideline, Alabama still covered the biggest spread of last week, winning by 63 over 57-point underdog Western Carolina. Favorites and underdogs split last week’s games featuring lines of three touchdowns or larger, with notable covering underdogs being Arkansas against LSU, Massachusetts against BYU, Purdue against Wisconsin and Kansas against Iowa State.

As with last Saturday, it’s hard to find any big underdogs this weekend capable of winning outright. Tennessee, which has covered four straight, should make quick work of 21-point underdog Vanderbilt. Colorado stunned Washington last week, but the Buffs are a 28-point dog at Utah — which has covered seven straight, many of those by healthy margins.

But as for potential underdog covers? Georgia has been winning ugly lately, and Georgia Tech has covered two of its last three. The Jackets host the Bulldogs as 28-point underdogs in Atlanta. South Florida was blown out last week by Memphis, but they played close, competitive games the two weeks prior against Temple and Cincinnati, and are 25-point underdogs at Central Florida.

And finally there’s Maryland, which has lost six straight and covered just once in that span — and it’s a 21-point underdogs against another bad Big Ten team, Michigan State, which has won one of its last six and covered once in its last seven. It’s enough to make you pine for Rutgers. Almost.

About the Author

David Caraviello for Bookies.com
David Caraviello
Veteran sports journalist David Caraviello has covered college football, college basketball, motorsports and golf, covering all three US golf majors, the Daytona 500 and SEC football.