Both the Cardinals and the Cowboys enter Week 17 with their playoff spot locked up. However, they are each fighting for seeding as it’s possible Dallas could still be the No. 1 seed in NFC, while the Cardinals could get as high as the No. 2 seed.

But just because these teams have clinched playoff berths doesn’t mean it won’t be an important, highly-intense game. The Cardinals absolutely need a win to keep pace in the NFC West after losing their last three games. Meanwhile, the Cowboys want to continue their positive momentum after four consecutive wins.

To get you ready for this NFC matchup, here is everything you need to know from an NFL betting perspective along with our NFL picks going into Week 17.

Check out the latest Cardinals vs Cowboys odds, betting lines, injury report and more.

Cardinals vs. Cowboys Matchups

Cardinals WR A.J. Green vs. Cowboys CB Trevon Diggs: Without DeAndre Hopkins, Green will be the de facto No. 1 receiver for the Cardinals. That means he’ll see a ton of Diggs in Week 17, who leads the NFL in interceptions with 11.

Cowboys WR CeeDee Lamb vs. Cardinals CB Byron Murphy: Lamb went over 1,000 receiving yards last week and now will be guarded by one of the league’s top slot cornerbacks in Murphy.

Cardinals QB Kyler Murray vs. Cowboys LB Micah Parsons: The matchup we all want to see is Murray vs. Parsons in the open field. These are two of the best athletes in the NFL who are both playing at an extremely high level.

RELATED: NFL Week 17 odds & Betting Lines For All Games

Cardinals vs. Cowboys Stats

20.4: The Cardinals have the No. 5 scoring defense, allowing only 20.4 points per game.

30.5: The Cowboys have the No. 1 scoring offense in the NFL, averaging 30.5 points per game.

150: The Cowboys have the second-best point differential in the NFL at +150.

7-1: The Cardinals are 7-1 ATS in their last eight road games.

10-0: The Cowboys are 10-0 ATS in their last ten games against NFC opponents.

Cardinals vs. Cowboys Moneyline

It feels like these two teams are going in opposite directions. The Cowboys have won four straight, covering the spread in every game. Meanwhile, the Cardinals have lost three straight games and have lost their lead in the NFC West. But does that mean you should bet on the Cowboys to win this game at home?

They are a -225 favorite at home on DraftKings and that’s probably not a bad bet. However, the play here is to bet on the point spread as there is a lot of value on the Cardinals, so take note Arizona sports betting fans.

Expect the Cowboys to win, but for this game to ultimately be close and be decided late in the fourth quarter. Our advice is to pass on the moneyline in favor of the point spread.

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Cardinals vs. Cowboys Point Spread

The Cowboys are 12-3 ATS this season, which is the best in the NFL. They have the second-best point differential in the NFL this season (behind only the Bills) and they have the look of a legit Super Bowl contender. However, the smart bet this week is to bet on the Cardinals to cover the spread. They are the more desperate team and they are getting back center Rodney Hudson, who has made a huge difference to their win/loss record.

Look for this to be a close game on Sunday that is likely decided by a late field goal. The Cowboys should win, but take the Cardinals +5.5 (-110) on DraftKings as the Cowboys are giving about two more points than expected. Expect this to be a 27-24 type of game in Dallas on Sunday.

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Cardinals vs. Cowboys Totals

As you would expect, the point total in this matchup between two NFC playoff teams is high. In fact, it’s the highest of the week at 52. No other game in Week 17 features a point spread of more than 49 points. However, 52 feels a bit high considering both of these teams rank inside of the top-10 in points allowed per defense.

Yes, the offenses are incredibly explosive. But we’ve seen a tendency from both of these teams to lean more on the run game and defense over the last few weeks. Look for this game to have a playoff-like atmosphere in which points are somewhat hard to come by. For that reason, take the Under 52 (-110) on FanDuel and expect this to be a 27-23 type of game in Dallas on Sunday.

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