There is one question looming over and throughout One Patriot Place this week – ahead of the Bills-Patriots game on Thursday night that begins Week 13 of the NFL betting season: “Will the Patriots force the Bills to punt?”

This query was not made in jest. The Patriots and Bills have played three times in the past 359 days. In those three games, the Bills have punted just five times. The Bills have not punted in their previous two games against New England, beating the Patriots by a combined score of 80-38 against the Bill Belichick & Sons coached defense. Things were particularly exceptional or ugly – depending on one’s perspective – when New England played Buffalo in the AFC Wild Card round on January 16. 

The Bills won 47-17. Buffalo scored on its first seven offensive possessions before taking a couple of knees to run out the clock in the fourth quarter. 

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The 6-5 Patriots have won on the back of their defense this season. But that defense was exposed by Kirk Cousins and the Vikings on Thanksgiving night.  

Buffalo is 8-3 but sits second in the AFC East because of a loss to 8-3 Miami earlier this season. The Bills have self-corrected after consecutive losses to the Jets and Vikings. They scored a combined 59 points in wins over Cleveland and Detroit. Josh Allen, however, has been banged up of late. And he’s been intercepted in the red zone in four of his past five games. There’s no doubt The Hoodie has digested that film and has a plan to replicate it. 

The Bills have moved from 2.5 to 4-point favorites at DraftKings Sportsbook with a -195 moneyline. The home underdog Patriots are +165 and the total is 43.5 points. There will be touchdowns. Just how many by New England remains the unknown. 

Best Anytime TD Scorer Prop Bets For Bills-Patriots

Here are our best TD scorer prop bets on sports betting apps for the Bills-Patriots game on Thursday night. Kickoff is scheduled for 8:15 p.m. ET on Amazon Prime and on local affiliates in each team’s home market. 

While it comes too late for this NFL season, Patriots fans should expect online Massachusetts sports betting to go live in the state around March 2023. So this time next year, these markets will be legal in the Bay State.

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Jakobi Meyers Anytime TD

1st Patriots TD Odds: +700 at DraftKings

Anytime TD Odds: +275 at DraftKings

The forecast calls for a windy Thursday in Greater Boston, with conditions supposedly calming down after dark. Otherwise, it will be a clear and chilly night. If the wind tempers as predicted, look for the Patriots to throw the ball much like they did against Minnesota indoors early, when that outcome was still in doubt. 

In that game, Hunter Henry scored the Patriots’ first TD. But Jakobi Meyers was hurt earlier. Meyers is expected to be back and fully healthy. He remains Mac Jones’ target of first choice. Finding Meyers in the end zone seems exactly the type of thing the Patriots are wanting to do when the world expects them to run the ball on every snap. 

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Rhamondre Stevenson Anytime TD

Anytime TD / NE Patriots to win Odds: +285 at DraftKings

Anytime TD Odds: -115 at DraftKings

The Bills will be loaded up to stop – or try to slow – Rhamondre Stevenson. But Stevenson is too good to keep out of the end zone. He’s got exceptional breakaway speed and could score from beyond the Red Zone. 

If you like the Patriots to win this game, this is a good way to grab a boost on the +165 moneyline. The Patriots can’t win without getting yards and points from their top running back. Certainly not against Buffalo. 

Josh Allen Anytime TD

Odds: +180 at BetMGM

The Bills don’t necessarily want Josh Allen to be running the ball as much as he has been of late. He’s banged up and they are thinking Super Bowl 57 or bust in Western New York. 

Allen’s rushing total is 44.5 yards in this game, and he’s not necessarily the first option for defenses in Red Zone situations. This is a good price. The battle between Matthew Judon and Allen will be one to watch all night. 

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Isaiah McKenzie Anytime TD

Odds: +290 at DraftKings

The essence of any Belichick & Sons defense is to take away your best weapon. The Patriots contained Dalvin Cook last week to 42 yards rushing on 22 attempts, only to be sliced up by Justin Jefferson. 

This week, they’ll be focused on containing Stefon Diggs. That leaves Isaiah McKenzie as the receiver most likely to be left alone in single coverage. McKenzie had six catches for 96 yards and a TD for Buffalo on Thanksgiving against Detroit. He’ll be open early and often again in Foxboro and should return to the end zone in Week 13.