Bills vs Panthers Same Game Parlay Picks for NFL (Oct 26th, 2025)

By Bookies.com Staff Oct 22nd, 2025 11:30 AM EDT

Buffalo Bills running back James Cook (4) tries to avoid Miami Dolphins linebacker Jordyn Brooks (20). Mark Konezny-Imagn Images

The calendar points to October 26th, and Bank of America Stadium draws attention with its pivotal NFL meeting. Carolina’s defense has faced challenges at home, especially with receivers finding space on key possessions. Buffalo enters this game with Josh Allen delivering multiple touchdown passes in five of his last six away games. James Cook has exceeded seventy rushing yards in four out of six appearances when traveling. Combined trends hint at compelling touchdown opportunities for both teams on the day. NFL same game parlay picks today.

Bills vs Panthers Same Game Parlay Picks (Oct 26th, 2025)

Selecting touchdown scorers from each side leverages player trends against mismatched defenses in this scenario. Rushing upside for James Cook aligns well with Buffalo’s red zone tendencies, while Josh Allen’s passing acumen adds another layer for the Bills’ attack. On Carolina’s end, Tetairoa McMillan’s knack for yardage at home justifies inclusion as a potential scorer.

Pick 1: Player Touchdowns – James Cook Over 0.5 – -140

James Cook has surged past seventy rushing yards in four out of his last six matches played outside Buffalo. His role expands when defenses focus heavily on preventing big plays through the air, often resulting in more carries near the goal line for him specifically during these types of matchups. Carolina's run defense has shown vulnerability at times this season which creates opportunities close to pay dirt if Buffalo sustains drives deep into opposing territory.

Pick 2: Player Touchdowns – Josh Allen Over 0.5 – +100

Josh Allen remains a central figure any time Buffalo visits an opponent's stadium thanks to direct involvement near scoring range almost every week lately; he produced at least two passing touchdowns five times across his past six such occasions away from home turf showcasing not only accuracy but also creative improvisation within broken plays that frequently lead to touchdowns either by arm or scrambling ability when pocket protection breaks down.

Pick 3: Player Touchdowns – Tetairoa McMillan Over 0.5 – +195

Tetairoa McMillan stands out among Panthers’ options because he exceeded forty receiving yards during six of seven previous appearances inside Bank of America Stadium indicating significant trust placed upon him by quarterbacks under pressure situations where quick release routes become crucial particularly within red-zone packages thus enhancing likelihood he finds himself open enough short-to-medium distances necessary for touchdown conversions even against aggressive coverage alignments favored by some opposing secondaries visiting Charlotte.

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