The Broncos and the Giants have both missed the playoffs for multiple season, but both teams believe they made the right moves this offseason to compete in their respective conferences. In Week 1, they face off as the Broncos will travel to New Jersey to take on the Giants. Both teams are incredibly strong on defense, but as usual, the quarterback position remains a massive question mark for both sides.

With both teams having a difficult schedule this season, it’s vital they get off to a fast start. But who should you be betting on in Week 1? Here is everything NFL betting fans need to know about Broncos vs Giants odds.

GET READY FOR THE SEASON: Week 1 NFL Betting Lines & Analysis For All 16 Games

Broncos vs. Giants Key Matchups

Giants LT Andrew Thomas vs. Broncos EDGE Von Miller: The Giants are counting on Thomas to take a step in Year 2, but he will be challenged in Week 1 against a fresh Von Miller.

Broncos WR Jerry Jeudy vs. Giants CB James Bradberry: The Giants have a Pro Bowl cornerback in Bradberry, but who does he cover in Week 1 between Courtland Sutton and Jerry Jeudy?

Broncos TE Noah Fant vs. Giants FS Jabril Peppers: The Broncos have weapons all over the field, so how will the Giants matchup with Fant in the middle of the field? Expect Peppers to draw that assignment early.

5 Key Broncos vs. Giants Stats

• Broncos lost 5 of their last 6 games to finish the 2020 season.
• Giants have failed to cover the spread in 7 of their last 8 games against AFC opponents.
• The under has hit in seven straight games for the Giants
• Broncos have lost 4 of their last 5 road games
• Giants have lost 12 of their last 15 games in September

Broncos vs. Giants Player Prop To Consider

Broncos WR Jerry Jeudy, to score a TD

Odds: +190 on DraftKings

One of the big winners of Teddy Bridgewater being named the starting quarterback is Jerry Jeudy, who developed a strong connection with his quarterback during camp. Jeudy is a precise route runner and Bridgewater can deliver the ball to him accurately and on time. Look for Jeudy to explode in Week 1 with Courtland Sutton still not quite fully healthy.

Bet $5, Get $150 Instantly

Tap for Promo Activated! Visit site

Used 34 Times Today

21+ and present in most states. (18+ DC/KY/NH/WY). Void in IA/KS/KY/LA/MD/MI/NJ/NY/TN/VA/VT/ONT. Eligibility restrictions apply. On behalf of Boot Hill Casino & Resort (KS). 1 per new customer. Min. $5 deposit. Min. $5 bet. Max. $150 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Terms: dkng.co/bball. Ends 1/5/25 at 11:59 PM ET. Sponsored by DraftKings. GAMBLING PROBLEM? CALL 1-800-GAMBLER, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD).

Broncos vs. Giants Moneyline

The Broncos are historically one of the league’s best teams when it comes to early-season matchups. However, that mostly only matters when they are playing in Denver in the altitude. But will they have the same success on the road?

Considering it is Week 1, it’s tough to pick against a home underdog, especially when you consider that both teams failed to even win eight games last year. And when you factor in the value, it makes it all the easier to take the Giants. We like the Giants to upset the Broncos at +140 at DraftKings as one of our favorite underdog NFL picks of the weekend.

Bet $5, Get $150 Instantly

Tap for Promo Activated! Visit site

Used 41 Times Today

21+ and present in most states. (18+ DC/KY/NH/WY). Void in IA/KS/KY/LA/MD/MI/NJ/NY/TN/VA/VT/ONT. Eligibility restrictions apply. On behalf of Boot Hill Casino & Resort (KS). 1 per new customer. Min. $5 deposit. Min. $5 bet. Max. $150 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Terms: dkng.co/bball. Ends 1/5/25 at 11:59 PM ET. Sponsored by DraftKings. GAMBLING PROBLEM? CALL 1-800-GAMBLER, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD).

Broncos vs. Giants Point Spread

If you are considering taking the Giants on the moneyline, you should think about betting them on the point spread. While the odds and payouts are lower, the extra 3 points that the Giants are getting at most sportsbooks and betting apps makes this appealing.

The Broncos are starting a new quarterback in Teddy Bridgewater and they’ve never been a strong road team to open the year. Add on the fact that they have several key guys coming off injuries and they are easy to fade in Week 1.

The Giants also have an underrated defense and could easily hold the Broncos under 20 points. Early on in the season, you’ll see several NFL spreads with home underdogs. This is a good time to jump on the value as we really don’t know which teams are good and bad yet. That’s why we like the Giants + 3 BetMGM as this projects to be a very tight contest.

Bet $5, Get $150 Instantly

Tap for Promo Activated! Visit site

Used 68 Times Today

21+ and present in most states. (18+ DC/KY/NH/WY). Void in IA/KS/KY/LA/MD/MI/NJ/NY/TN/VA/VT/ONT. Eligibility restrictions apply. On behalf of Boot Hill Casino & Resort (KS). 1 per new customer. Min. $5 deposit. Min. $5 bet. Max. $150 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Terms: dkng.co/bball. Ends 1/5/25 at 11:59 PM ET. Sponsored by DraftKings. GAMBLING PROBLEM? CALL 1-800-GAMBLER, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD).

Broncos vs. Giants Totals

Believe it or not, the Giants finished inside of the top-10 in scoring defense last season, giving up just 22 points per game. They’ve somehow managed to improve their defensive roster this year, adding players such as Adoree Jackson and Azeez Ojulari. This should be a really good unit again and the Broncos certainly don’t have the look of a high-powered offense.

This is likely to be a defensive struggle, with the winning team probably scoring in the low 20s. Be sure to check out your favorite betting sites for the best odds, but we like the Under 42.5 at FanDuel.

Bet $5, Get $150 in Bonus Bets if Your Bet Wins + 3 Free Months of NBA League Pass

Tap for Promo Activated! Visit site

Used 36 Times Today

Must be 21+ and present in OH. Gambling Problem? Call 1-800-GAMBLER.