The marquee matchup of NFL Week 12 odds features two of the best teams in the league, as the Rams will travel to Green Bay to take on the Packers. Both teams have legit Super Bowl aspirations this season and are all-in on winning a championship.

The winner of this game will be in prime position to be challenge the Cardinals for the No. 1 seed in the NFC, while the loser might already have one loss too many to make up. Needless to say, this is a very critical and important game for both sides, and a tough one when deciding on your NFL picks.

Betting sites and most betting apps see this as a pick’em-type game. What do we think? Here is everything you need to know from an NFL betting perspective on this huge game.

Take a look at Rams vs Packers odds, injury report, betting lines and more.

Rams vs. Packers Matchups

Packers WR Davante Adams vs. Rams CB Jalen Ramsey: The best receiver in the league against the best cornerback in the league. What could be better?

Rams WR Cooper Kupp vs. Packers CB Chandon Sullivan: Kupp primarily plays in the slot, so look for Sullivan to be the man tasked with stopping the NFL’s leading receiver.

Packers LG Jon Runyan vs. Rams DT Aaron Donald: If the Packers have one weakness, it’s their interior offensive line. Unfortunately, Donald can dominate even the best offensive lines in the NFL. He has a chance to wreck this game from the side on Sunday.

Rams vs. Packers Stats

6-1: The Packers’ record ATS in their last seven games against NFC opponents

0-7: The Rams’ record ATS in their last seven games against the Packers

9-1: The Packers’ mark ARS in their last 10 games this season

1-6: The Rams have lost six of their last seven games against the Packers

1: Home losses by the Packers in their last 11 home games

Rams vs Packers Weather

It will be Packers weather in Lambeau. High of 37°F with no precipitation expected. Mild wild gusts between 10-15 mph with temperatures dropping to the upper 20s by the end of the game.

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Rams vs. Packers Moneyline

There is a real possibility that these are the best two teams in the NFC right now. While the Rams are on a two-game losing skid, they might just have the best roster in the NFL. The offense hasn’t played well over the last two weeks, but the hope is that their Week 10 bye is what they needed to get back on track.

Meanwhile, the Packers are the NFL’s best home team and have Aaron Rodgers under center. Green Bay just doesn’t lose at home very often, and especially not against NFC opponents. Their roster is beat up, but home field advantage and No. 12 make a big difference in games like this. Take the Packers on the moneyline at Caesars Sportsbook against the Rams and expect them to get another home victory.

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Rams vs. Packers Point Spread

If you like the Packers on the moneyline at sportsbooks, you might as well take them against the spread, as well. On most sites, they are somewhere between a pick’em or a -1 point favorite. Green Bay should be able to win this game as the Rams have struggled in Green Bay under Sean McVay in the past.

They just don’t have the type of team that plays well outdoors on the road. Take the Packers -0.5 points on PointsBet and expect them to get this win and stay in the hunt for the No. 1 seed in the NFC.

Rams vs. Packers Totals

This game has all the makings of a shootout in Green Bay, and NFL odds reflect that. The Packers are missing multiple defensive starters, and the Rams would love nothing more than to show off their new toy in Odell Beckham Jr.

Meanwhile, the Packers haven’t had that game yet where they score a ton of points. Although, they are coming off their most productive offensive game of the season in Week 11. Look for both teams to score in the upper 20s on Sunday. Take the OVER 47.5 on DraftKings and expect a 31-28 type of game in Green Bay.

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