As they face the Los Angeles Rams on Sunday, it’s the game that Detroit Lions fans have simultaneously circled on the calendar and been dreading all season long. The NFL betting on this game really shouldn’t be about two players, but circumstances assure that it will be.

Rams QB Matthew Stafford and Lions QB Jared Goff were traded for each other in the offseason. While Stafford has proven a perfect fit in LA for the 5-1 Rams, with each passing week, Goff appears to be the square peg seeking to squeeze into a round hole for the 0-6 Lions.

At NFL betting sites, the Rams are whopping 14.5-point home favorites.

Check out the latest Lions vs. Rams odds ahead of the matchup on Sunday.

Lions vs Rams Key Matchups

Matthew Stafford vs Jared Goff: Both chosen No. 1 overall in their draft year, Stafford is at the helm of the 5-1 Rams, while Goff is under center for the 0-6 Lions. Stafford is third in the NFL in TD passes (17). Goff is 22nd (7). Stafford is second in the NFL in passer rating (116.6). Goff is 23rd (86.9).

Rams Offense vs Lions Defense: LA rates No. 6 in the NFL in terms of total offense (2,406 yards). The Lions are No. 28 (2,307) in total defense. The Lions are 20th at stopping the pass (1,514). The Rams are the No. 4 passing offense (1,785).

Lions Offense vs Rams Defense: Flip the script and the storyline is equally bad for Detroit. LA is the NFL’s No. 11-rated defense (2,202). Detroit is No. 27 on offense (1,926). The Lions offense hasn’t run a play from scrimmage with the lead in a game all season long.

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5 Key Lions vs Rams Stats

7: TD receptions by Rams WR Cooper Kupp. He had three all last season.

9: Straight losses by Lions QB Goff, a career high.

20: The Rams have scored at least 20 points in each of the first six games of the season for just the second time in franchise history.

9.1: Yards per pass attempt by the Rams, which is the best in the NFL.

9.8: Yards allowed per pass attempt by the Lions, which is the worst in the NFL.

Lions vs Rams Weather Forecast

Maybe it’s the black cloud that seems to follow the Lions everywhere, but Sunday’s weather forecast isn’t bringing the typical Southern California sunshine for Detroit’s first-ever visit to play the Rams at SoFi Stadium. Expect there to be cloudy skies, 6 mph wind and a game-time temperature of 66 degrees.

Lions vs Rams Player Props

Rams QB Matthew Stafford, Over 288.5 passing yards

Odds: -115 at BetMGM

Stafford is averaging 306.3 yards per game through the air this season.

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Lions QB Jared Goff, Under 236.5 passing yards

Odds: -115 at PointsBet

Goff is averaging 202.5 yards per game the past two weeks.

Rams TE Tyler Higbee, Over 38.5 receiving yards

Odds: -115 at DraftKings

Higbee is averaging 48 yards per game in three home games this season.

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Lions vs Rams Moneyline

LA’s only loss this season was at home, but it was against the Arizona Cardinals, the NFL’s only 6-0 team. It’s hard to imagine that they’ll fall on their home field to the NFL’s only 0-6 team. Going back to last season, the Lions have lost 10 consecutive games. They are 3-8-1 in their last 12 games played in the Pacific time zone.

Detroit hasn’t won a game in the state of California since beating the Oakland Raiders 28-27 on Dec. 18, 2011. That being the case, betting apps have LA at -1000 in the moneyline. At those odds, the bet simply isn’t worth the risk.

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Lions vs Rams Point Spread

The 14.5-points is the largest in NFL spreads assigned against the Lions over the past five seasons. However, it’s the third time that Detroit is a double-digit underdog in a game already this season.

The Lions are 1-1 against the spread in that scenario in 2021, but just 1-5 ATS in their last six games as a double-digit underdog. The Rams are 4-3 ATS in their last seven games in which they’ve been a double-digit favorite. That includes Dec. 2, 2018, when they won 30-16 at Detroit as the 10-point chalk. It seems foolhardy to give an NFL team 15 points, but it’s the Lions we’re talking about. Lay the points and take the Rams. You can get the Rams -14.5 (-110) at DraftKings.

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Lions vs Rams Totals

LA is the No. 6 scoring offense in the NFL (29.8 points per game). The Rams have scored at least 27 points in five of six games and 34 or more in three games. They are 3-0 on the total at home this season. The total has gone over in six of LA’s last eight games.

The Lions are at the other end of the spectrum. They are 2-4 on the total this season. Detroit’s last four games have all gone under. Again, the total of 50.5 in the NFL picks might make you lean under, but this has high-scoring affair written all over it. Play the over. You can get Over 50.5 at FanDuel.

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