Raiders vs Chargers Picks & Predictions for MNF NFL Week 4

Adam Thompson | 10 mins

NFC West rivals head into Monday Night Football with a ton of momentum, as Justin Herbert and the Los Angeles Chargers host Derek Carr and the Las Vegas Raiders for a Week 4 prime-time showdown. The Raiders are a surprising 3-0 after an OT win over the Dolphins, while the Chargers (2-1) must avoid a letdown after winning at Kansas City in Week 3.
Betting sites and betting apps have installed L.A. as 3.5-point favorites, with an Over/Under of 52.5 points in the latest Raiders vs. Chargers odds. But is this among the NFL spreads to attack or avoid?
Check out the latest Raiders vs. Chargers odds, betting lines, injury report and more.
Raiders vs. Chargers Key Matchups
Raiders RBs vs. Chargers DL: No team has allowed more yards on the ground than L.A., which has surrendered 170 per game. Vegas has three backs with the potential to break loose.
Darren Waller vs. Chargers LBs: Waller leads all tight ends with 20 receptions, and his 224 yards is second only to Travis Kelce. L.A. ranks 25th in yards allowed to TEs so far.
Williams/Allen vs. Raiders Secondary: Mike Williams (22 receptions) and Keenan Allen (21) are one of just two WR teammates with 20 receptions apiece so far. Las Vegas ranks 27th in receptions allowed to wideouts.
5 Key Raiders vs. Chargers Stats
1: The win streak by the Chargers over the Raiders, thanks to a 30-27 OT win last December. Since 2002, only once has a “streak” of one not been extended to two.
3.4: The yards per rush for the Raiders. Only the Rams, Texans and Steelers are lower.
5.8: The yards per rush allowed by the Chargers – easily the highest in the NFL.
51.3: The points per game in the last four Raiders-Chargers matchups. Both games last season totaled 57 points.
401: The pass yards per game for Derek Carr, nearly 40 yards more than second-place Tom Brady. Justin Herbert is fourth at 319 ypg.
RELATED: NFL Week 4 Odds & Analysis For Every Game
Raiders vs. Chargers Player Props To Back
Mike Williams, Over 75.5 Receiving Yards
Odds: -115 at DraftKings ➜
Sure, the Raiders rank sixth in pass defense. But that’s not going to stop Justin Herbert from slinging it. His top option these days is Williams, who has had no fewer than seven receptions, and no fewer than 82 yards in any game this season.
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Darren Waller, Over 67.5 Receiving Yards
Odds: -115 at DraftKings ➜
Waller is a unique talent at tight end, and a tough cover for any team. He’s averaging 74.7 ypg already, and the Chargers are bottom 10 covering tight ends.
Waller, Allen, Williams Each 50+ Receiving Yards
Odds: +220 at FOX Bet ➜
Doubling down on Waller and Williams and adding Keenan Allen, who is averaging 86 yards receiving per game. Someone would have to have a real down game to miss this one, and I see this game as a pass-happy shootout.
Austin Ekeler, Under 13.5 Rushing Attempts
Odds: -135 at Caesars ➜
I’m sure the Chargers will want to establish some run against a Raiders defense that ranks 22nd vs. the run. But eventually this game will be a tit-for-tat throwing exhibition. Ekeler averages only 11.7 rushes per game, and 10 per game the last two weeks.
Derek Carr, Over 35.5 Pass Attempts
Odds: -115 at DraftKings ➜
Carr hasn’t thrown fewer than 37 passes in any game this season. He’s averaging 45.3 attempts. Eventually this game devolves into only throws for Vegas.
RELATED: NFL Week 4 Picks & Best Bets For Every Game
Raiders vs. Chargers Weather Forecast
Highs will reach the lower 80s on Monday, and it’s Los Angeles; it’s expected to be sunny with no real threat of rain. Nighttime temps are likely to drop into the upper 60s by the end of the game. SoFi Stadium has a canopy, so the players and fans will be protected from whatever elements may be outside.
Raiders vs. Chargers Moneyline
The Chargers are at -200 on the moneyline, meaning it would take a $200 wager to win $100 in profit. Conversely, the underdog Raiders are +170 (a $100 win means $170 in profit). It’s a moneyline spot that sportsbooks are enticing fans of both sides to consider.
The Raiders may be unbeaten, but two of the wins came in overtime. Carr may lead the NFL’s top passing attack, but the defense has let lesser QBs produce. There isn’t much value on the host Chargers, either, given their penchant for games decided in the final minute.
Raiders vs. Chargers Point Spread
The Chargers are at -3.5 on the point spread, with an enticing hook on an underdog Raiders team with an offense that can move the ball. But which is best to add to your Week 4 NFL betting Monday night lineup?
In the six combined games these teams have played this season, all of them have been decided by six points or less. Herbert has been impressive, but this is also a team that ranks dead-last vs. the run and near the bottom of running itself. Either team can win at the end, however, so the points are too good to give up. The Raiders have covered four straight on Monday night. Vegas +3.5 is the best bet if adding MNF to your NFL picks lineup. You can get the Raiders +3.5 (-110) at BetMGM ➜.
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Raiders vs. Chargers Totals
The Over/Under for Monday Night Football sits at 52.5, the third-highest total for NFL Week 4. It features offenses averaging a combined 720 yards of pass offense per game. Who’s going to take the Under with firepower like that?
Trends suggest that might be the way to go. The Under is 16-4-1 in the last 21 meetings in Chargers home games and is 4-0 the last four instances when the Chargers were favored. Most Raiders trends point to the Over, however, and that is the play for this Monday as well. You can get O53 at DraftKings at -110 ➜.
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