NFC West rivals face off in a marquee Thursday Night Football matchup, as Russell Wilson and the Seattle Seahawks host Matthew Stafford and the Los Angeles Rams. The teams come into the NFL Week 5 TNF showdown after contrasting Week 4 results – Wilson’s Seahawks downed the 49ers in San Francisco last Sunday, while Stafford’s Rams were hammered at home by the Cardinals.

Sportsbooks have Los Angeles as a 1.5-point road favorite, after betting sites and top betting apps moved from the opening line of -1.

Check out the latest Seahawks vs. Rams odds, betting lines, injury report and more.

Rams vs. Seahawks Key Matchups

Darrell Henderson vs. Seahawks Defense: The Rams RB could be in for a big day here against a Seattle 11 that ranks 31st in rush yards allowed and 32nd in receiving yards to backs.

Seahawks WRs vs. Rams DBs: L.A. is lauded for its cornerbacks. They rank 30th in receptions allowed but only 21st in yards allowed.

Russell Wilson vs. Rams Defense: Wilson has averaged 222 yards per game passing in 18 career games vs. L.A., 38 yards under his average the last three years.

RELATED: NFL Week 5 Odds & Betting Lines For All Games

5 Key Rams vs. Seahawks Stats

2.0: The yards per carry difference between Darrell Henderson (4.9) and anyone else who has run the ball for the Rams (2.9).

4: Passing TDs allowed by the Rams through four games. Only four teams have allowed fewer through four weeks.

40: Combined receptions for Seattle WRs Tyler Lockett and DK Metcalf. Each has 20 catches so far, while nobody else on the team has more than nine.

197.8: Yards allowed from scrimmage by running backs against the Seahawks defense, easily the most in the NFL.

302: Yards allowed by the Rams against opposing tight ends. Only the Ravens and Chiefs have allowed more.

Rams vs. Seahawks Weather Forecast

Players and fans can expect a brisk evening in Seattle at Lumen Field. The rain should hold off, but temps for kickoff will be around 50 degrees and could drop into the 40s by the second half.

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Top Rams vs Seahawks Player Props

Russell Wilson, Over 20.5 Rushing Yards

Odds: -118 with FOX Bet

Chris Carson (neck) should play but won’t be 100%. Alex Collins stepped up last week in Carson’s limited action, and Wilson should also get his share of rushing tries. He’s only hit Over this total once in four games, but it was last week. Expect the pocket to break down more than once vs. the Rams.

Chris Carson, Under 13.5 Rushing Attempts

Odds: -110 with DraftKings

Carson has received 12-13 carries in each of the last three games but hasn’t practiced leading up to this Thursday game. Expect a bigger dose of Collins, and of passing, against L.A.’s 26th-ranked pass D.

Robert Woods, Under 60.5 Yards

Odds: -115 with BetMGM

Only once in four games has Woods hit this mark, and he required nine targets in that game to get to 64 yards. Every other game, he’s received 4-6 targets. With other weapons and a run game that should find success vs. Seattle, Woods is likely to finish Under yet again.

Rams vs. Seahawks Moneyline

The Rams are around -120 on the moneyline, meaning a $120 wager would win $100 in profit. On the other side, Seattle is at +110 (+100 wins $110 in profit).

The Rams have had the Seahawks’ number over the years and are poised for a bounce-back game here. Seattle’s defense has too many holes against an L.A. offense. This is a fair price for the favored Rams, even on the road. You can back the Rams at BetMGM.

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Rams vs. Seahawks Point Spread

NFL spreads this small are similar to simply picking a winner. Los Angeles is favored with the spread at only -1.5. That might be surprising considering what happened last week. But the Rams have covered the spread in four of the last five meetings between these teams.

That is the side to take here, too. L.A.’s offense, especially, has the firepower to score a lot of points against what is statistically the worst defense in football. Wilson will get his, but the Rams’ overall talent surpasses what Wilson can do. Those looking for a Thursday night side as part of your NFL picks should back Stafford and the Rams. You can get the Rams -1.5 (-114) at FanDuel.

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Rams vs. Seahawks Totals

The Over/Under for Thursday Night Football is 54.5 points, up from the opening line of 53 points set on Sunday. Only the Week 5 Sunday Night Football matchup between the Bills and Chiefs has a higher total than this one.

This line may not be low enough. These teams know how to move the ball, and they’ve struggled to stop the opponent from doing the same. The Seahawks and Rams rank in the bottom-six in total defense. The Over has hit in the last six Rams games and in four of the last five meetings between these teams in Seattle. Consider the Over as part of your NFL betting Week 5 lineup. You can get Over 54 (-110) at DraftKings.

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