The final games of the regular season are here and while there are a number which have no impact on how teams finish, this one is very important to the Cardinals, who need a win to be in with a chance of taking the NFC West title away from the Rams, although betting sites think that is unlikely with Arizona available at +340 at BetMGM to take top spot in the West.

With their season over, the Seahawks finally had a productive offensive performance putting up 50 points against the Lions last week. Will this be Russell Wilson’s final game in a Seahawks uniform? It’s going to be an offseason of rumors surrounding his future.

A win for the Cardinals last week kept alive their chance of winning the West and with the 49ers beating the Rams in the last five matchups between the two, a win here for the Cardinals could take the division and secure a home playoff game for Kliff Kingsbury’s team. It would be the perfect finish to a great regular season for Arizona sports betting fans.

Let’s take a look at the odds to assist your NFL picks on the game.

Take a look at Cardinals vs Seahawks odds, injury report, betting lines and more.

Seahawks vs Cardinals key matchups

Kyler Murray vs. Seahawks defense: Most QBs are the key to their team but it’s especially important for the Cardinals, especially with James Conner and Chase Edmonds carrying injuries. It could mean a lot more designed runs for Kyler in this one.

Rashaad Penny vs. Cardinals run defense: Rashaad Penny is finally proving his worth as a 1st round draft pick. He has the most yards on the ground over the last four weeks and scored twice last weekend. The Cards are a top-10 run defense so it will be tough this week.

Cardinals pass offense vs. Seahawks secondary: The Cardinals have struggled to adjust since losing DeAndre Hopkins, but the emergence of Antoine Wesley alongside A.J. Green and Christian Kirk showed up last week. They are up against the fifth-worst passing defense so they should move the ball through the air.

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Key Seahawks vs Cardinals stats

170: Number of yards Penny had last week against the Lions.

48: Average rush yards for Kyler Murray since the start of December.

173: Games Russell Wilson has started for the Seahawks.

3-4: Cardinals' home record this season, they are 8-1 on the road.

1-4: O/U record between these teams in the last five games between the two.

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Seahawks vs Cardinals Moneyline

With the difference in results and performance this season, the moneyline is understandably one-sided towards the Cardinals, according to the NFL betting. The best price available for the home team is -275 at BetMGM.

The Cardinals need the win so we know they’ll be pushing, but this is a nothing game for the Seahawks. Would they really mind the Cardinals winning the division over the Rams? If you think they’ll pull off the shock then you can get +240 at TwinSpires. After the last month for the Cardinals, I wouldn’t be surprised to see the Seahawks win here.

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Seahawks vs Cardinals Point Spread

Obviously we prefer to bet against the NFL spread and you can find the Cardinals at around a touchdown favorite. The good thing for us is that the sportsbooks are offering 7 and 6.5, depending on which side you want to bet.

The Cardinals are 10-6 against the spread this season, although only 2-5 at home. The Seahawks are 4-4 on the road so this all comes down to how motivated you think they will be. I like the Seahawks +7 at -115 with DraftKings.

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Seahawks vs Cardinals Totals

The Cardinals defense ranks as a top-10 unit this year, while the offense has stumbled at times this season. The last five games between these two (since Kingsbury joined the Cardinals) have resulted in four Unders, although the one Over came in a 71-point thriller.

This Seahawks team has struggled for most of the year with Russ unable to cook but they finished their home schedule with a big game last week. I think they come back down to earth this week. Checking the betting apps, I like Under 48, best priced at -110 with Caesars.

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