Arguably the best game on Sunday will feature two All-Pro quarterbacks returning to the lineups of their respective teams. Russell Wilson is back after missing the last three games due to a broken finger. Seattle is just 3-5 and they need their franchise quarterback to help them win games and get back into the playoff conversation in the NFC.

Meanwhile, Aaron Rodgers is expected to clear COVID-19 protocols on Saturday, paving the way for him to start in Week 10. Rodgers missed last week’s game against the Chiefs after testing positive early last week.

How will both quarterbacks look in their return to the field? And which team’s defense will step up and make big stops in key moments? To get you ready for this huge NFC matchup, here is everything you need to know from an NFL betting perspective going into Week 10.

Take a look at Packers vs. Seahawks odds, injury report, betting lines and more.

Seahawks vs. Packers Matchups

Packers WR Davante Adams vs. Seahawks CB D.J. Reed Jr.: Adams might be the best receiver in the league and should have a big mismatch over Reed. Don’t be surprised if Adams goes over 100 yards and scores multiple touchdowns in this contest.

Seahawks WR D.K. Metcalf vs. Packers CB Kevin King: Metcalf will benefit the most from having Russell Wilson back in the lineup and will have a big mismatch against King on Sunday.

Seahawks C Ethan Pocic vs. Packers DT Kenny Clark: Clark is one of the league’s best and most underrated interior defenders. He should wreck havoc against Pocic and the Seahawks OL this week.

RELATED: NFL Week 10 Odds & Betting Lines For All Games

Seahawks vs. Packers Stats

22.1: The Packers have the No. 20 scoring offense in the NFL, averaging only 22.1 points per game.

1-4: The Seahawks are just 1-4 SU against the Packers in their last five meetings.

8-0: The Packers are 8-0 ATS in their last eight games.

21.1: The Seahawks have the No. 9 scoring defense in the NFL, allowing just 21.1 points per game.

5-0: The Packers are 5-0 ATS in their last five games against NFC opponents.

Seahawks vs. Packers Player Props

Seahawks WR D.K. Metcalf, Over 69.5 Receiving Yards

Odds: -115 at DraftKings

Metcalf benefits the most from Russell Wilson’s return. He should have multiple deep receptions on Kevin King in this matchup.

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Packers RB A.J. Dillon, Under 41.5 Rushing Yards

Odds: -115 at DraftKings

With Aaron Rodgers back, Dillon’s role will likely be decreased. He should still see some work as a receiver, but fewer than 10 carries.

Seahawks QB Russell Wilson, Over 1.5 Passing Touchdowns

Odds: -140 at DraftKings

The Packers pass defense will be without multiple starters and Wilson will need to score into the upper 20s to win this game. Look for at least two touchdowns from him in his return to the field.

RELATED: NFL Week 10 Picks & Best Bets For Every Game

Seahawks vs. Packers Moneyline

Simply put, the Packers are a better team than the Seahawks. Even when Russell Wilson is healthy, the Seahawks have had a lot of problems getting wins. Now, they will face the Packers in Green Bay and that has historically been a bad matchup for Seattle.

We have no idea how much Wilson’s finger injury will impact his ability to throw the ball and the rest of the team just isn’t good enough to carry the Seahawks to a victory. Take the Packers (-165 at DraftKings) and expect them to get another win over Seattle in Week 10. Don't forget to shop around on betting sites and betting apps for the best NFL odds, as they may change closer to kickoff.

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Seahawks vs. Packers Point Spread

With Aaron Rodgers back under center for Green Bay, this might just be the best team in the NFL. While the offense hasn’t dominated yet, the defense has been surprisingly good this season. They are allowing only 20 points per game and just held Patrick Mahomes and the Chiefs to 13 points in Kansas City.

The defense should be able to force a few turnovers in this game and keep Wilson under control. With this game being in Green Bay, it’s one the Packers should win more often than not. Take the Packers -3 (-110) on BetMGM as one of your NFL picks and expect Green Bay to win a close and competitive game on Sunday.

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Seahawks vs. Packers Totals

Despite neither offense ranking inside of the top-15 in points per game this season, this is one of the highest over/unders of the week at 49.5-50 with most major sportsbooks. That isn’t all that surprising considering how good both Russell Wilson and Aaron Rodgers have been over their careers.

But both quarterbacks are coming back to the field after missing a few weeks. It’s fair to expect some rust despite these two being some of the best quarterbacks in NFL history. Take the Under 50 (-110) on FanDuel and expect a 24-21 type of game.

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