Tennessee Titans vs Jacksonville Jaguars Predictions, Best Bets & Picks

By Adam Thompson Mar 14th, 2024 7:22 AM EDT

Tap for Promo Visit site

Get Up To $100 Back In FanCash If Your Football Bet Loses for 20+ Gamedays In A Row

Used 48 Times Today

21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MI, NC, NJ, OH, PA, TN, VT, VA, WV, or WY. Must sign up by 9/30/25. Apply offer in bet slip; place $1+ American football cash wager w/ odds +300 or longer each Game Day. Wager must settle as loss to qualify for FanCash equal to the amount of losing wager (up to $100 FanCash per Game Day). Rewards expire 10/31/25. Terms, including FanCash terms apply-see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA).

The playoffs begin one week early for the Tennessee Titans and Jacksonville Jaguars, as the teams face off with the AFC South title on the line in a Saturday night primetime showdown. 

The winner between Derrick Henry’s Titans (7-9) and Trevor Lawrence’s Jaguars (8-8) receives the automatic postseason berth for winning the division. The season is likely over for the loser (the Jags have a very slim 6% to 8% chance of clinching a wild card if they lose to Tennessee but results go their way on Sunday). 

The Jaguars are home for this one and are on a four-game win streak, a run that began with a 36-22 win at Tennessee. Jacksonville is favored by six points on NFL betting sites in the latest Titans vs. Jaguars odds, with an Over/Under set at 40 points. 

Bookies.com NFL handicapper Adam Thompson – who has hit on over 62% of his NFL picks in each of the last three years – reveals his best plays for the win-or-go-home clash. 

Titans vs. Jaguars Point Spread Prediction

Two teams heading on different trajectories. The Titans have lost six in a row. Fans wanting Ryan Tannehill out have now seen how valuable he is compared to the alternatives. Henry is a beast but the Jags can put eight in the box with Joshua Dobbs under center. 

Jacksonville has won four straight, scoring 31-plus in three of those games. While Jacksonville is strong vs. the run, Tennessee has the NFL’s bottom-ranked pass defense. It’s Jacksonville’s time. Lay the points on the home favorite on sports betting apps. 

Tap for Promo Visit site

Get Up To $100 Back In FanCash If Your Football Bet Loses for 20+ Gamedays In A Row

Used 48 Times Today

21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MI, NC, NJ, OH, PA, TN, VT, VA, WV, or WY. Must sign up by 9/30/25. Apply offer in bet slip; place $1+ American football cash wager w/ odds +300 or longer each Game Day. Wager must settle as loss to qualify for FanCash equal to the amount of losing wager (up to $100 FanCash per Game Day). Rewards expire 10/31/25. Terms, including FanCash terms apply-see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA).

Titans vs. Jaguars Over/Under Best Bet

The total of 40 points is 1.5 points lower than the last time these teams faced off, a game that totaled 58. The Under has cashed in three straight Titans games and in two Jags games in a row. Tennessee’s offense without Tannehill has scored 17, 17, 14 and 13 points. 

Can the Jaguars put up enough to get to the Over? Against this defense, absolutely. The Over is a secondary play consideration. 

Titans vs. Jaguars Moneyline Prediction

The Jaguars are -255 on the moneyline, so it would take a $255 wager on Jacksonville to win $100 in profit on sports betting sites. The Titans are +215. 

We like Jacksonville to cover the six-point spread, but they also have home losses to the Broncos, Giants and Texans. Those were in the first half of the season, but this is a young team and Henry is coming at them. All of Jacksonville's four wins during this run have been by six-plus and averaged 16 ppg. We’ll stay on the spread. 

Tap for Promo Visit site

Get Up To $100 Back In FanCash If Your Football Bet Loses for 20+ Gamedays In A Row

Used 48 Times Today

21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MI, NC, NJ, OH, PA, TN, VT, VA, WV, or WY. Must sign up by 9/30/25. Apply offer in bet slip; place $1+ American football cash wager w/ odds +300 or longer each Game Day. Wager must settle as loss to qualify for FanCash equal to the amount of losing wager (up to $100 FanCash per Game Day). Rewards expire 10/31/25. Terms, including FanCash terms apply-see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA).

Best Titans vs. Jaguars Player Props

Trevor Lawrence, Over 255.5 Pass yards

Odds: -115 at BetMGM

The emerging Lawrence carved up the Tennessee last-ranked pass defense for 368 yards in a 36-22 win just a few weeks ago. Don’t expect much different here, now at home with a playoff berth on the line. The Titans have allowed more pass yards than any team and at least 266 yards in five of the last six games. Jacksonville is 7-4 when Lawrence goes over 180 pass yards. 

Tap for Promo Visit site

Get Up To $100 Back In FanCash If Your Football Bet Loses for 20+ Gamedays In A Row

Used 48 Times Today

21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MI, NC, NJ, OH, PA, TN, VT, VA, WV, or WY. Must sign up by 9/30/25. Apply offer in bet slip; place $1+ American football cash wager w/ odds +300 or longer each Game Day. Wager must settle as loss to qualify for FanCash equal to the amount of losing wager (up to $100 FanCash per Game Day). Rewards expire 10/31/25. Terms, including FanCash terms apply-see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA).

Derrick Henry, Over 90.5 Rushing Yards

Odds: -115 at DraftKings

Henry has gained 121, 104 and 126 yards in the last three games despite no semblance of a Titans pass attack to take the pressure off. In 12 career games vs. the Jaguars he’s averaged 105.3 ypg. Tennessee is undefeated (4-0) when Henry gets 25 carries. The team’s best shot is to hammer all night long. 

About the Author

Adam Thompson

More About Adam

Long established as one of the nation's premier handicappers, Adam Thompson joined Bookies.com in 2019 after a successful run as senior handicapper for SportsLine & CBSSports.com. He specializes in the NFL and MLB, where he's hit on well over 60% of his picks the past five years. Adam's NBA and horse racing picks have also produced consistent, major winners over the years.