One of the most impressive wins in Week 1 by any team was by the Arizona Cardinals. They dominated the Titans in the trenches and Kyler Murray had one of his best games of his career. In Week 2, they’ll host the Minnesota Vikings.

The Vikings are coming off a tough overtime loss, as they had 116 penalty yards and a key fumble in overtime to give the game to the Bengals.

Can the Cardinals continue their early-season success or will the Vikings even their record at 1-1? Here is everything you need to know about this NFC matchup from an NFL betting perspective, as well as our Week 2 NFL picks.

RELATED: NFL Week 2 Odds & Betting Lines and be sure to check out more Cardinals vs. Vikings odds.

Vikings vs. Cardinals Key Matchups

Cardinals WR DeAndre Hopkins vs. Vikings CB Patrick Peterson: Teammates from a year ago, Peterson really struggled in Week 1. Can he bounce back against a receiver that he practiced against every day last season?

Vikings WR Justin Jefferson vs. Cardinals CB Marco Wilson: The weakest part of the defense for the Cardinals is their secondary, but they held up well against A.J. Brown and Julio Jones last week. Can they stop Justin Jefferson and Adam Thielen in Week 2? That will be quite the test.

Vikings LT Rashod Hill vs. Cardinals DE Chandler Jones: Jones had five sacks in Week 1. The Vikings better plan on helping Hill on every snap this week if they want to contain Jones.

5 Key Vikings vs. Cardinals Stats

8: The Vikings have failed to cover the spread in eight straight games.

4 of 5: The Under has hit in four of the last five games for the Cardinals.

5-1: The Vikings are 5-1 against the Cardinals in their last six meetings.

1-6-1: The Cardinals are 1-6-1 straight up against the NFC North in their last eight games.

5 of 6: The Over has hit in five of the last six games for the Cardinals at home.

RELATED: NFL Week 2 Odds & Betting Lines For All 16 Matchups

Vikings vs Cardinals Player Prop Bets

Cardinals RB Chase Edmonds over 72 total yards ( -110 on DraftKings : Edmonds saw 16 touches in Week 1, and that game was a blowout. Look for the Cardinals to get him even more touches as he should easily go over this yardage total. Don’t be surprised if he goes over 70 rushing yards alone.

Vikings WR Justin Jefferson over 71.5 receiving yards ( -110 on DraftKings : Jefferson had a quiet Week 1, catching five passes for 71 yards. He should have an even better game against Arizona as the Cardinals lack strong outside cornerbacks. Jefferson should come close to 100 yards.

Cardinals WR A.J. Green under 39.5 receiving yards( -110 on DraftKings : The Cardinals have so many weapons that there just aren’t a ton of targets for Green. Look for Kyler Murray to spread the targets around and for Green to potentially be left out some this week.

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Vikings vs. Cardinals Moneyline

While it seems easy just to take the Cardinals on the moneyline here, the Vikings aren’t as bad as they showed in Week 1. A number of penalties and miscues made that game a lot closer than it should have been and the Vikings can be much better on offense.

However, Minnesota’s offensive line is a bit of a problem and they might not have the answers to slow down Chandler Jones and J.J. Watt. This is a game that will likely be closer than anyone anticipates, but the smart bet here is to still wager on the home team. Take the Cardinals (-225) on DraftKings .

Vikings vs. Cardinals Point Spread

NFL spreads tend to be a bit off in Week 2. Generally, sportsbooks and betting sites will set big lines, hoping to catch bettors overreacting.

I think that’s the case here in Week 2 as the Vikings and Cardinals aren’t all that different from one another. This feels like a field goal game that is likely decided on the final possession. It’s important to remember that even despite Arizona’s big win in Week 1, they are just 3-7 ATS in their last 10 games.

They aren’t used to being the betting favorite either, which is why the Vikings are the better pick here. Take the Vikings +4.5 (-110) on FanDuel .

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Vikings vs. Cardinals Totals

The total for this game is set at 51, which is one of the highest in Week 2. That makes sense considering both offenses can be explosive. However, that is a monster line considering how inconsistent both sides can be on a week-to-week basis.

Look for the Vikings to try to establish the run, which should keep their defense off the field. Both teams should score in the low-20s, but not quite enough for the over to hit.

Take the Under 51 points (-105) at BetMGM in this NFC matchup. Be sure to shop around for the best price on your favorite NFL betting apps as this line will surely move throughout the week.

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