Week 13 of NFL betting includes a few leftover turkeys but has a delicious entree atop the menu. That would be a delectable matchup in the NFC that could ultimately determine home-field and the top seed in the playoffs.  

The San Francisco 49ers return to the East Coast this week to play the NFL-best Philadelphia Eagles. This game is not only a rematch of last season’s NFC title game, but a possible preview of the sequel this season. The Detroit Lions and Dallas Cowboys may have something to say about that.

The Eagles are 10-1 after knocking Kansas City and Buffalo in a span of six days. Jalen Hurts has tush-pushed his way into the MVP conversation. The 49ers and Brock Purdy have returned to their 2022 form. They feasted on roasted Seahawk on Thanksgiving night. 

The Broncos and Texans meet in a “surprise these teams are in the playoff discussion” game. 

That game was flexed out of its original 4:05 p.m. slot so it could be the CBS national game at 1 p.m. 

RELATED: Super Bowl 58 Odds

The Cowboys and Seahawks begin the week on Thursday night. This game will likely play a role in the final seeding for both teams as they are likely headed for a wild card. The Seahawks face a tough road test after losing 31-13 to the Niners at home.

The main reason for this week’s otherwise diluted schedule: 6 teams are on the bye. 

FOX will air the aforementioned 49ers-Eagles game as its national offering at 4:25. 

The Epta-Box returns to NFL RedZone this week with 7 games in the 1 p.m. Sunday slot. The Chiefs and Packers play on Sunday night. While the Jaguars play host to Joe Burrow-less Bengals on Monday. 

Bye: Ravens, Bills, Bears, Raiders, Vikings, Giants

2023 NFL Week 13 Picks 

Now it’s on to our Week 13 NFL picks to back on your favorite sports betting app. 

2023 NFL Week 13 Best Bets To Back Today

Thursday, Nov. 30

Seattle Seahawks at Dallas Cowboys, 8:15 p.m. (Prime Video)

The Seahawks will have to show they can beat better teams on the road if they want to advance in the playoffs. A sizable chunk of the viewing audience may be distracted by the season finales of “The Golden Bachelor” and the penultimate episode of “Bachelor In Paradise.” Both teams have a full week off heading into this Thursday night game. 

The offensives should be fully operational. But this total has jumped 2.5 points since last week. The Cowboys, meanwhile, keep crushing big numbers. They've covered double-digit lines three weeks in row. We'll sweat the hook. 

Best Bet: Dallas -7.5 (-110) with DraftKings Sportsbook

Up to $1,500 in Bonus Bets if Your First Bet Loses Promo Code: BOOKIES

Tap for Promo Activated! Visit site

Used 44 Times Today

Bonus Bets Expire in 7 Days. One New Customer Offer Only. Must be 21+ to participate & present in OH. In partnership with MGM Northfield Park. Gambling problem? Call 1-800-GAMBLER. Visit BetMGM.com for T&Cs. US promotional offers not available in NY, NV, or Puerto Rico.

Sunday, Dec. 3

Los Angeles Chargers at New England Patriots, 1 p.m. (CBS)

The Patriots have a nasty history of beating the Chargers at the worst times – for the Chargers. But those Patriots have been assigned to the dustbin of history. 

This line has spiked from 4 to 6.5 points in the past 48 hours ahead of Monday morning. The Patriots are in danger being unable to stop and/or keep up with the Chargers in this one. Even with the early East Coast start. Still, the Patriots are 8-3 on the under this season. Let's roll with that until further notice. 

Best Bet: Under 41.5 Points (-110) with DraftKings Sportsbook

Bet $5, Get $150 in Bonus Bets if Your Bet Wins + 3 Free Months of NBA League Pass

Tap for Promo Activated! Visit site

Used 19 Times Today

Must be 21+ and present in OH. Gambling Problem? Call 1-800-GAMBLER.

Detroit Lions at New Orleans Saints, 1 p.m. (FOX)

The Lions were caught napping on Thanksgiving by the Packers. The Saints won't have such luck, especially after Detroit's extended break. The Saints didn't score a touchdown in their 24-15 loss to the Falcons Sunday. 

The Lions offense should be able to regain its footing. The Lions will push to establish their running game. This number is a bit of discount, even with the hook. 

Best Bet: Lions -3.5 (-110) with DraftKings Sportsbook

$1,000 First Bet on Caesars Promo Code: BOOKIES1000

Tap for Promo Activated! Visit site

Used 13 Times Today

Must be 21+ to participate. T&Cs apply.

Atlanta Falcons at New York Jets, 1 p.m. (FOX)

The Jets will have an extended break following their Black Friday affair playing host to Miami. It’s too soon to be pondering any sort of an Aaron Rodgers comeback. The Jets should be able to stifle the Falcons, who have also cycled through multiple quarterbacks this season. Throw in some bad weather and share a laugh. We took this total when it was 36.5. Still, 34 is not unreasonable here. 

Best Bet: Under 34.5 Points (-110) with DraftKings Sportsbook

Bet $5, Get $150 Instantly

Tap for Promo Activated! Visit site

Used 61 Times Today

21+ and present in most states. (18+ DC/KY/NH/WY). Void in IA/KS/KY/LA/MD/MI/NJ/NY/TN/VA/VT/ONT. Eligibility restrictions apply. On behalf of Boot Hill Casino & Resort (KS). 1 per new customer. Min. $5 deposit. Min. $5 bet. Max. $150 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Terms: dkng.co/bball. Ends 1/5/25 at 11:59 PM ET. Sponsored by DraftKings. GAMBLING PROBLEM? CALL 1-800-GAMBLER, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD).

Arizona Cardinals at Pittsburgh Steelers, 1 p.m. (CBS)

Run, Kyler. Save yourself. The Steelers have covered in 8 of 9 against losing teams. Mike Tomlin once again has his team in playoff contention in December. 

Best Bet: Steelers -6 (-110)  with DraftKings Sportsbook

Indianapolis Colts at Tennessee Titans, 1 p.m. (CBS)

If the season ended today, your Indianapolis Colts would be in the playoffs. Buffalo and Cincinnati would not. How's that for parity. Or is it parody. Garnder Minshew knows how to win. 

He's let the Colts to three straight victories and put them over .500 and in the postseason picture. The Titans are running out the string on Mike Vrabel's term as head coach. The Colts have moved from +1 to -2 here. The moneyline is a good price, for now. 

Best Bet: Colts ML (-130) with DraftKings Sportsbook

Up to $1,500 in Bonus Bets if Your First Bet Loses Promo Code: BOOKIES

Tap for Promo Activated! Visit site

Used 29 Times Today

Bonus Bets Expire in 7 Days. One New Customer Offer Only. Must be 21+ to participate & present in OH. In partnership with MGM Northfield Park. Gambling problem? Call 1-800-GAMBLER. Visit BetMGM.com for T&Cs. US promotional offers not available in NY, NV, or Puerto Rico.

Miami Dolphins at Washington Commanders, 1 p.m. (FOX) 

This number has swelled from Miami -7 to -10.5 points. That's understandable given how both teams played in Week 12. It will be seasonbaly warm with mild wind and slight rain on Sunday. So the weather won't bother Miami's South Beach offense. (Yes, we know Hard Rock Stadium is well inland amid the scrub-brush that marks the Miami-Dade/Broward county line.) 

The total is steep, but these teams are averaging 51 points per game. You might want to consider buying a half-point on the spread at this price. Still, the Dolphins are 3-1 this season against lines greater than 9 points. This one could be out of reach at halftime. 

Best Bet: Dolphins -10 (-105) with DraftKings Sportsbook

Bet $5, Get $150 in Bonus Bets if Your Bet Wins + 3 Free Months of NBA League Pass

Tap for Promo Activated! Visit site

Used 41 Times Today

Must be 21+ and present in OH. Gambling Problem? Call 1-800-GAMBLER.

Denver Broncos at Houston Texans, 1 p.m. (CBS) 

Surprise! Surprise! Both of these teams are legitimate contenders for the postseason. The Broncos are the hottest team in the AFC, having won 5 straight.  The Texans have developed a knack for close-come-from-behind victories in the final minute. Houston missed a tie at the gun against Jacksonville Sunday when Matt Amendola's kick doinked off the center crossbar. Hence the tight line here. 

The Texans have been making money for the books, having failed to cover in 7 straight as favorites. We can certainly envision a last-second Houston win here - by 1 or 2 points.

Best Bet: Broncos +3 (-105) with DraftKings Sportsbook

$1,000 First Bet on Caesars Promo Code: BOOKIES1000

Tap for Promo Activated! Visit site

Used 58 Times Today

Must be 21+ to participate. T&Cs apply.

Carolina Panthers at Tampa Bay Buccaneers, 4:05 p.m. (CBS) 

The Panthers are enjoying an extended exhibition season in preparation for 2024. They began the housecleaning on Monday morning by firing coach Frank Reich. Given the state of the NFC South, the Buccaneers are a default playoff contender. Neither offense has been shown to be very effective at this point of the season. 

But Baker Mayfield showed some life in Tampa Bay's Week 12 loss. Tampa Bay's defensive front will do its part in pushing Bryce Young toward reaching that elusive season sacked record. The Panthers don't travel well to the Sunshine State, having failed to cover in their past 6 games in Florida. 

Best Bet: Buccaneers -6 (-110) with DraftKings Sportsbook

Bet $5, Get $150 in Bonus Bets if Your Bet Wins + 3 Free Months of NBA League Pass

Tap for Promo Activated! Visit site

Used 59 Times Today

Must be 21+ and present in OH. Gambling Problem? Call 1-800-GAMBLER.

Cleveland Browns at Los Angeles Rams, 4:25 p.m. (FOX) 

The Rams once played in Cleveland. The Browns (7-4) have moved into playoff contention this season despite a revolving door at quarterback. The Browns lost QB Dorian Thompson-Robinson and WR Amari Cooper to injury in their Week 12 loss at Denver. Cleveland’s defense is stout. 

The Rams should be able to contain the Browns QB Du Jour. This line has spiked from Rams -1 to -4.5. Which we all know is closer to 7 than 3. While the Rams looked terrific in Week 12, they are consistently inconsistent and have failed to cover at home 9 straight times after a win. 

Best Bet: Browns +4.5 (-110) with DraftKings Sportsbook

San Francisco 49ers at Philadelphia Eagles, 4:25 p.m. (FOX) 

This week’s “Game of the Year” features a rematch of last season’s NFC championship game. The Eagles knocked out Brock Purdy and the 49ers and earned a ticket to Super Bowl 57. If Purdy can stay ambulatory, the 49ers will contend. The Eagles defense was hidden from most of the nation until their Monday night win at Kansas City in Week 11. It was able to contain the Bills in the rain Sunday night. Two impressive backt-to-back wins in 6 days. 

The winning QB of this game will have the inside track for MVP honors. Jalen Hurts has taken a quantum leap in his development this season. The Eagles are on a heater against winning teams at the Linc, having won 11 straight. They're getting points here. 

Best Bet: Eagles +2.5 (-102) with DraftKings Sportsbook

Up to $1,500 in Bonus Bets if Your First Bet Loses Promo Code: BOOKIES

Tap for Promo Activated! Visit site

Used 33 Times Today

Bonus Bets Expire in 7 Days. One New Customer Offer Only. Must be 21+ to participate & present in OH. In partnership with MGM Northfield Park. Gambling problem? Call 1-800-GAMBLER. Visit BetMGM.com for T&Cs. US promotional offers not available in NY, NV, or Puerto Rico.

Kansas City Chiefs at Green Bay Packers, 8:20 p.m. (NBC) 

Will Taylor Swift bundle up for a visit to America’s Dairyland? Well, her "Eras" tour film is going to streaming on her birthday - Dec. 13 - and she's off the road until next year. This game is on national TV. NBC loves it some TS. So we think, "yes." The Chiefs are a solid bet this season on the under, going 8-3. Weather could be an issue here. 

Best Bet: Under 42.5 Points (-105) with DraftKings Sportsbook

Monday, Dec. 4 

Cincinnati Bengals at Jacksonville Jaguars, 8:15 p.m. (ABC/ESPN) 

Trevor Lawrence vs. Jake Browning! This game was originally billed to serve as a matchup between two former No. 1 draft picks at quarterback. But Joe Burrow is out for the season. 

He’s been replaced by former undrafted free agent Browning. This one doesn’t quite have the same ring to it. The Jaguars are looking to lock up the AFC South ASAP. All the AFC divisional leaders are in the hunt for the first-round bye. It's going to do down to late on the afternoon of January 8. Jacksonville has covered in 5 straight. 

Best Bet: Jaguars -7.5 (-110) with DraftKings Sportsbook