This is the weekend where college basketball dreams meet their ultimate fate. Just one win separates these teams from a Final Four appearance in New Orleans, and we’ve got an outstanding, versatile slate of college basketball betting matchups.

Looking around at betting sites for March Madness we’re in the mood for an Elite Eight weekend parlay.

Our last two parlays have cashed on betting apps – including a +570 Sweet 16 hitter. Let’s keep it going with a third straight in the Elite Eight.

RELATED: Today's Best March Madness Picks & Predictions To Back

Best NCAA Tournament Parlay for Elite Eight

College basketball odds accurate as of publication. Make sure to check out our DraftKings promo code page before placing your wagers.

Bet $5, Get $200 Instantly + Score a No Sweat Parlay Every Day

Tap for Promo Activated! Visit site

Used 39 Times Today

GAMBLING PROBLEM? CALL 1-800-GAMBLER, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD). 21+ and present in most states. (18+ DC/KY/NH/WY). Void in ONT/OR/NH. Eligibility restrictions apply. On behalf of Boot Hill Casino & Resort (KS). 1 per new customer. Min. $5 deposit. Min. $5 bet. Max. $150 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Terms: dkng.co/ftball. Ends 2/9/25 at 11:59 PM ET. Sponsored by DK.

Leg 1: Houston-Villanova Under 128

These two teams are among the most methodical in the country. They control the game by limiting possessions, getting it done with precision and efficiency. They’re elite on the defensive end and won’t get flustered at any point. Villanova’s best chance to win is to go even uglier than the Cougars, who were absolutely rolling on offense in Thursday’s upset win over No. 1 Houston. We don’t know if the strategy will work, but we think we’re in for a low-scoring grind. We’re on Under 128 for the opening leg.

RELATED: 2022 March Madness Ultimate Betting Guide

Leg 2: Duke ML over Arkansas

Duke is the better team with more skill, and the Blue Devils have looked unstoppable halfway through the Big Dance. But we love this Razorbacks team and all the experience in the backcourt. The Arkansas guards were relentless and answered the bell against Gonzaga every single time. Duke is the tougher challenge, in our opinion, one that Arkansas won’t quite be able to pass – even if they cover the +4 point spread. We’re on Duke moneyline -180

Leg 3: Miami +6 over Kansas

The Hurricanes were way too much for Iowa State to handle. They looked like a Final Four team in that win Friday night, draining 3s while keeping things open in the paint. It was a beautiful display. Kansas will be Miami’s best tournament opponent by a long shot and we don’t know if the Hurricanes can pull off the upset to knock off the last remaining No. 1 seed. We just know they have the size and skill to match up where it matters and give Kansas all it can handle. We’re rolling with Miami +6 to bring it home in the final leg.