The Week 3 NFL slate gets going Thursday night in an AFC South game between the visiting Tennessee Titans and the host Jacksonville Jaguars. Let’s take a look at some of the best bets fans of NFL betting should consider:

Titans-Jaguars Best Bets

All odds current as of publication but subject to change.

PICK 1: Jaguars Moneyline

I get that the Titans have owned the Jaguars in recent years. Tennessee has won six of the past seven games. I also realize the Titans have looked better than the winless Jaguars. But these two teams are pretty even, especially if Tennessee quarterback Marcus Mariota doesn’t play or is hobbled by a quad injury that he suffered in a loss to the Indianapolis Colts in Week 2.

It’s a short week, and even if he does play, Mariota may not be at full strength. If he can’t go, backup Ryan Tannehill will start. The Jaguars are coming off of a bitter defeat in Houston in Week 2. Jacksonville coach Doug Marrone went for two points in the final seconds instead of attempting a PAT to send the game to overtime.

So, the Jaguars are probably thrilled to get back on the field on a short week to move on from the sting of the Houston game. Getting the home team at a good price on the moneyline is the way to go here.

RELATED: Check Out Our Complete Titans-Jaguars Betting Preview

PICK 2: Under 40

This bet makes sense for a few reasons. The early Thursday night trend is the under this season. Both Thursday night games – Green Bay at Chicago in Week 1 and Tampa Bay at Carolina in Week 2 – have gone under. Also, both of these teams played low-scoring games in Week 2. The Titans lost 19-17 to the Colts and the Jaguars lost 13-12 to the Texans.

And then there’s the quarterback situations. If Tannehill plays, the line could go down a few points. Even if Mariota does play, he may not be at full strength, which, of course, will affect Tennessee’s offense. Also, Jacksonville rookie quarterback Gardner Minshew (pictured above) – who is playing for the injured Nick Foles – has been good as he has completed 45 of 58 passes.

Yet, the Jaguars are still having trouble scoring. Plus, the Titans have a strong defensive coaching staff. It may be too much for Minshew to handle on a short week. The under seems like the smart play again this Thursday night.

PICK 3: Jaguars & Under 40

This bet is simply all about me feeling good about the home team and the under. The Mariota factor and the fact that Jaguars are due for a win are the reasons why I’m backing Jacksonville. So, at this strong price, I like this parlay bet.

PICK 4: Under 3.5 Total TDs

This prop bet is about feeling great about the under. We’re banking on the trends from Week 2 with these two teams and the reality of a short week. Plus, the quarterback issues. At +160, this is a great bet.

PICK 5: Jaguars 1st-Quarter Winner

Expect the Jaguars to come out determined to put on a better swing at home than they did in Week 1 against the Chiefs. Even if Mariota plays, the Titans may be slow to get going. We like the Jaguars getting the better of the field-position game early and taking the lead after the first quarter.

PICK 6: No Team to 20 Points

See a trend here? We don’t foresee many points being scored. Both teams played in games that didn’t hit the 20-point mark in Week 2, and we feel strongly about that happening when they meet Thursday. The point spread (Tennessee is 1.5-point favorites at most sportsbook) and the 40-point total suggest that this is a very possible outcome. Plus, +290 is a worthy play.

Check Out Other NFL Games Latest Betting Odds:

• Bills vs Jets
• Cowboys vs Redskins
• Dolphins vs Jets