AFC contenders in desperate need of a victory face off in a key Week 7 Thursday Night Football matchup, as the Cleveland Browns host Teddy Bridgewater and the Denver Broncos.

The Browns have dropped two straight games by allowing 47 and 37 points and will be without most of their key offensive weapons, including QB Baker Mayfield. The Broncos have lost three in a row after starting 3-0. Each comes in at 3-3; a win could go a long way to playoff goals, a loss damages postseason goals and tiebreaker needs.

Sportsbooks have Cleveland as a two-point home favorite, this after most betting sites and some top betting apps opened the game at Browns -6.

Check out the latest Browns vs. Broncos odds ahead of the matchup on Thursday Night Football.

Broncos vs. Browns Key Matchups

David Njoku vs. Broncos LBs: The Browns TE leads the team in receptions, yards and touchdowns. Denver has yet to allow a TD to a tight end this season.

Courtland Sutton vs. Browns DBs: Only the Colts have allowed more TDs to receivers than Cleveland. Sutton has five TDs for Denver, nearly half the team’s receiving total.

Case Keenum vs. Everyone: Keenum hasn’t started a game since 2019, when he went 1-7 with Washington.

RELATED: NFL Week 7 Odds & Betting Lines For All Games

5 Key Broncos vs. Browns Stats

0: The combined rushing yards for D’Ernest Johnson and Demetric Felton – likely the top RBs on the depth chart with Nick Chubb and Kareem Hunt out.

3.7: The average yards allowed per rush attempt by both the Browns and Broncos, a top-five ranking.

5.2: The Browns’ average yards per rush attempt, tops in the NFL. That noted, Cleveland averaged only 3.7 rpg last week while the Broncos, at 4.6 on the season, are 5.6 over the last three games.

13.3: Over Cleveland’s last 30 games in which it rushed for under 90 yards in the previous week, the Browns have covered the spread just four times in their next game, just 13.3%. They had 73 yards rushing in their Week 6 loss to the Cardinals.

92.3: The Broncos have beaten the Browns in 12 of the last 13 meetings, a 92.3% win rate that dates back to 1991.

Broncos vs. Browns Weather Forecast

Thursday night is the start of a chilling trend expected in northern Ohio, and it begins with rain and a possible storm during the day. Temperatures, expected to be in the upper 60s during the day, dip into the 50s for kickoff with wind and a chance of rain.

Broncos vs. Browns Player Props

Teddy Bridgewater, Over 0.5 Interceptions

Odds: +100 at DraftKings

Bridgewater has thrown four INTs, but all of them were in the last two games. And now here comes a Browns team that ranks No. 2 in QB pressures and No. 2 in QB knockdowns, all while blitzing far less than most teams. Bridgewater has been pressured more than any other QB who has started all his team’s games.

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Case Keenum, Over 220.5 Pass Yards

Odds: -110 at Caesars

The Browns will be without Nick Chubb and Kareem Hunt, and their two starting offensive tackles, and are up against the NFL’s fourth-ranked rush defense. By default, if the Browns are going to get close to 300 total yards of offense, it’s going to be through the air. Cleveland still has good pass-catchers on the field.

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Odell Beckham Jr., Jarvis Landry, Courtland Sutton 50+ Receiving Yards Each

Odds: +175 at FOX Bet

Keenum must rely on Cleveland’s top WRs, each should see considerable targets. Landry had 71 yards in the only full game he’s played, Beckham has had 70-plus in two of four so far. Each should see more action with the best rushing attack in the league out of order. Sutton is the go-to for Bridgewater with 120 and 94 yards the last two games.

Broncos vs. Browns Moneyline

The Browns are -130 on the moneyline, meaning a $130 wager would win $100 in profit. On the other side, the Broncos are at +110 ($100 wins $110 in profit). Prior to the Mayfield announcement, the Browns were at -200, the Broncos at +170.

While most games come down to matchups, the Browns’ injuries are too critical to ignore. The team was missing both offensive tackles and star RB Nick Chubb vs. Arizona, and on this short week none of them will return. Mayfield and RB Kareem Hunt were injured last Sunday and are also out. Denver has its own injury issues, but Cleveland’s offense is going to struggle. Denver offers value on the moneyline and you can get them +108 at FanDuel.

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Broncos vs. Browns Point Spread

When it comes to NFL spreads, neither of these teams have added to a bankroll the last few weeks. The Broncos were favored in each of their last three straight-up losses, and the Browns are 0-2 ATS in their streak too.

The injuries might be too much to overcome for the Browns offense, especially vs. a Denver defense that should be motivated for a big bounce-back performance. Those looking for a Thursday night side as part of your NFL picks should lean with the road Broncos at +2.

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Broncos vs. Browns Totals

The Over/Under for Thursday Night Football is a very modest 41 points, down from the opening line of 44.5 and from 43 before Mayfield was declared out.

Regardless of the disappointing efforts of both defenses lately, the Under makes sense here. Each team has allowed points due to turnovers, but when it comes to yards allowed, the Browns are No. 2 in the NFL, the Broncos No. 4. Thursday night has been for offensive underachievement, with the Under hitting in four straight TNF games. Consider the Under here as part of your NFL betting Week 7 lineup.

You can get Under 41.5 (-110) at BetMGM.

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