Teams with something to prove face off on Monday Night Football when Drew Brees and the New Orleans Saints host the Los Angeles Chargers.

The Saints, one of the top NFC title contenders, are 2-2 coming off a win at Detroit. The Chargers are 1-3 and QB Tyrod Taylor has been shelved for rookie Justin Herbert.

The Chargers are 3-0-1 against the spread in their past four road games, but the Saints have crushed lesser foes, covering in 20 of their last 28 against sub-.500 teams. Let’s take a look at some of the best bets fans of NFL betting should consider:

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Best Chargers-Saints Odds & Props To Back

NFL odds listed are current as of publication and subject to change.

Chargers +8.5

This is a tough line for a home team that may not actually be home – we’ll see what Hurricane Delta decides. The Saints haven’t crushed anyone, using a pick-6 to beat the Bucs by 11, edging the Lions by 6 and dropping their other two games. The Chargers are just 1-3 but none of the losses were by this much. The Saints’ defense has been spotty, as has Drew Brees, who has notoriously failed to look downfield much. Find the best odds for the spread at FanDuel.

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Chargers-Saints Under 51

The Chargers lost Austin Ekeler so the Saints can focus more on Herbert, potentially limiting L.A.’s scoring potential. The Saints have scored at will, but the Chargers have a defense. Every Saints game has totaled at least 57 points. Three of the four Chargers games have finished at 43 points or less. Look for defenses to contain, or at least slow, the opposition. Secure the top Under price at DraftKings.

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Justin Herbert – Over 300 Yards

Herbert has made an immediate impact on the offense. It hasn’t led to wins, but it has led to robust stats. The rookie’s “worst” start accounted for 290 passing yards. The Saints allow 250 ypg through the air. Without Ekeler, expect Herbert to throw 40-plus times. Get the highest odds for the QB prop over at PointsBet.

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Shortest TD – Over 1.5 Yards

Only twice has the Saints scored from 1 yard. They’ve allowed a whopping four 1-yard scores, but the Chargers don’t have a single TD from the shortest distance. Not only that, they haven’t allowed one. In fact, there hasn’t been a 2-yard TD in any Chargers game. Lock in the best odds for the TD prop at BetMGM.

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Hunter Henry – Over 75 Yards

Henry accounted for 73 and 83 receiving yards in the Chargers’ first two games, but has been held in check the last two. Expect more passing from L.A. and more looks for the talented TE. The Saints are allowing an average of 5.2 receptions for 74.5 yards to opposing tight ends. Get the highest odds for the Henry prop with PointsBet.