At the start of the season, this looked like a game worth circling on the calendar. The Buffalo Bills, coming off their best season in decades, facing an up-and-coming Miami Dolphins team that was 10-6 in 2020.

The 4-2 Bills are still looking like legit Super Bowl contenders. The 1-6 Dolphins, on the other hand, have gone completely off the cliff. In NFL betting lines, Buffalo is a 13.5-point home favorite over Miami.

Check out the latest Bills vs. Dolphins odds ahead of the matchup in Week 8.

Dolphins vs Bills Key Matchups

Josh Allen vs Tua Tagovailoa: True, the quarterbacks don’t face each other, but how they fare goes a long way toward determining the outcome. Allen’s passer rating is 103.6. Tagovailoa is at 95.1. In seven starts against Miami, Allen has thrown for 19 TDs against 5 INTs.

Buffalo’s Red Zone Offense vs Miami’s Defense: No NFL team made more trips inside the opponent's 20-yard line in the season's first six weeks, but the Bills scored TDs only 55.2% of the time, 26th in the league and down from last season’s 62%. Will Miami’s dismal defense solve this problem?

Bills Takeaways vs Dolphins Giveaways: Winning the turnover battle is a key to unlocking victory in the NFL. Buffalo owns an NFL-leading +11 takeaway ratio. Miami is -2.

RELATED: NFL Week 8 Odds & Betting Lines For All Games

5 Key Dolphins vs Bills Stats

414.9: Number of yards per game being surrendered by Miami’s NFL-worst defense as the Dolphins face Buffalo’s No. 6 NFL offense (411.5 ypg).

6-0: Buffalo’s record coming off the bye week since 2015.

5: Receiving TDs by Miami RB Myles Gaskin in the past nine games. He had none through his first 15 NFL games.

2: Shutouts posted this season by the Bills. One came against the Dolphins.

7: Interceptions thrown by Tagovailoa over the past five games. He had two picks through his first nine NFL games.

Dolphins vs Bills Weather Forecast

If you’re the Dolphins, the best news is that you get to play at Buffalo in October. Sure, it’s the last day in October, but even Halloween in Buffalo isn’t as frightful as a December game at Buffalo. Sunday’s forecast at Highmark Stadium is for rain, 21 mph wind and a temperature of 53 degrees.

RELATED: NFL Week 8 Picks & Best Bets For Every Game

Dolphins vs Bills Player Props

Bills WR Stefon Diggs over 84.5 receiving yards

Odds: -115 at DraftKings

Diggs has gone over this total in two of the past three games.

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Bills QB Josh Allen over 282.5 passing yards

Odds: -115 at DraftKings

Allen passed for more than 300 yards each of the last two games.

Bills WR Emmanuel Sanders over 53.5 receiving yards

Odds: -115 at DraftKings

Sanders has bettered this total four games in a row.

Dolphins vs Bills Moneyline

Buffalo has covered the moneyline wager in the NFL picks five out of six games. The Bills are 2-1 in the moneyline at home this season, while the Dolphins are 1-2 on the road. The Bills have won six in a row and eight of the last nine games from the Dolphins.

At Buffalo, the Bills have been winners of four straight over Miami and eight of the last nine games. Against all opponents, Miami has lost each of its last six games. Buffalo is 9-1 in its last 10 home games. Miami is 1-4 in its last five road games. Still, Buffalo -900 simply isn’t a worthwhile wager. Pass on the moneyline.

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Dolphins vs Bills Point Spread

In their last two games against Miami, Buffalo won 35-0 earlier this season and 52-26 to close out the 2020 NFL regular season. In fact, as much as 13.5 points might seem like a significant amount to be laying in the NFL spreads, in reality the Bills have covered that line in three of the last four games when facing the Dolphins.

Buffalo already covered this season as 18.5-point home favorites against the Houston Texans. Miami is 5-5 against the spread the last 10 times the club was a double-digit underdog at betting sites. The Dolphins are reeling right now. Lay the points and take the Bills at DraftKings (-13.5) .

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Dolphins vs Bills Totals

No matter who they play, no matter where they play, the Bills just put points up on the board. The total established for this game at online sportsbooks is 49.5 points, which seems somewhat low. Buffalo is the NFL’s No. 2 scoring offense (33.8 points per game).

The Bills have scored over 30 points in five straight games and at least 40 in two of those games. Buffalo is 3-3 in the over/under this season, while Miami is 4-3. The best bet at NFL betting apps on this one is to play the over. You can get Over 49.5 (-110) at BetMGM.

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