San Francisco 49ers 2025 NFL Draft Odds: Who Will They Trade At No.11?

The San Francisco 49ers were extremely disappointing in 2024. After going all the way to the Super Bowl and losing overtime to the Kansas City Chiefs the season before, the 49ers were expected to make the playoffs again last year. But things went backwards for the 49ers, with the team regressing to 6-11 and finishing dead last in the NFC West.

After such a bad season, the 49ers have been busy this offseason, trading and cutting several of their veterans as the team looks to retool and become a contender once again.

Armed with the No. 11 pick in the 2025 NFL Draft, the 49ers have the opportunity to get a nice young player to help them regain relevance. With the draft fast approaching, Bookies.com veteran oddsmaker Adam Thompson has put together hypothetical NFL odds for sports betting on who the 49ers will take at No. 11.

2025 San Francisco 49ers NFL Draft Odds Pick 11

This hypothetical NFL betting market is for entertainment purposes only and does not reflect any market that may be available on betting sites and betting apps.

49ers Top 5 Picks

Mykel Williams, Edge, Georgia (+400)

The 49ers could use some help on edge, making Mykel Williams of Georgia a solid bet for the team to be picked at No. 11 if he’s still available for them to select.

Josh Simmons, T, Ohio St. (+450)

Starting left tackle Trent Williams turns 37 this year and missed seven games last year due to injury. That’s why the 49ers need to look at young tackles in the draft, including Josh Simmons of Ohio State.

Will Johnson, CB, Michigan (+450)

If Will Johnson of Michigan is still on the table at No. 11, the 49ers could consider him for their draft pick as they need help in the secondary, and he would certainly help them there.

Jalon Walker, Edge, Georgia (+650)

Jalon Walker of Georgia is another edge player who the 49ers could pick, should he be available.

Kelvin Banks Jr., T, Texas (+700)

Kelvin Banks Jr. of Texas is another viable option for the 49ers if they want to take a tackle in the first round.

Related: New York Jets 2025 NFL Draft Odds

Other Contenders

Nick Emmanwori, S, So. Carolina (+900)

Should the 49ers look to improve their secondary, they could consider Nick Emmanwori of South Carolina with the No. 11 pick.

James Pearce Jr., Edge, Tennessee (+1000)

Another option for edge would be James Pearce Jr. of Tennessee if the 49ers choose to help their defensive line out in the first round.

The Field (+500)

After letting go of so many players from last year’s roster, the 49ers have holes everywhere, and the field is a very likely option for them to make their pick.