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Sunday Night Football Betting Preview: 49ers At Seahawks

Geoff Mosher for Bookies.com

Geoff Mosher  | 4 mins

Sunday Night Football Betting Preview: 49ers At Seahawks

The NFC West title and more hangs in the balance for the final Sunday night showdown of the regular season.

The 49ers can wrap up the NFC West and secure a first-round bye along with home-field advantage with a win against the rival Seahawks, but a loss would knock 49ers into a wild-card berth and first-round road game.

The 49ers already lost to the Seahawks at home earlier this season, losing 28-25 to have their eight-game win streak to open the season snapped.

In NFL betting, the 49ers are favored at most sportsbooks by 3 or 3.5 points. You can compare the latest 49ers-Seahawks odds from top sportsbooks here.

RELATED: 5 49ers-Seahawks Prop Bets & Betting Lines To Back

The struggling Seahawks can finish strong by knocking off the 49ers again to win the NFC West. It’s unlikely they can still clinch home-field advantage throughout the playoffs, but if the Packers and Saints both lose, the Seahawks would jump into the top seed by defeating the 49ers.

The Seahawks limp into this showdown having lost running back Chris Carson, the NFL’s fifth-leading rusher, for the rest of the season with a hip injury. Seattle also lost running back C.J. Prosise and were already without first-round pick Rashaad Penny, leaving the run-reliant Seahawks without their three best running backs.

The Seahawks will also be without left tackle Duane Brown, who had surgery to repair a torn meniscus and is out a couple of weeks. On the positive side, defensive end Jadeveon Clowney (core muscle) is expected to return after missing the past two games.

Seattle brought back Marshawn Lynch and Robert Turbin, both of whom will have to be productive in this game for Seattle to win. The Seahawks have lost two of their last three and has failed to score 14 points in each of its two losses.

The 49ers are 2-2 over their past four games, with impressive wins over the Saints and Rams but losses to the Ravens and Falcons. They’re not nearly as banged up as Seattle is.

Betting 49ers-Seahawks Against The Spread

Sunday Night Football Betting Preview: 49ers At Seahawks 1
Wide receiver Emmanuel Sanders has given the 49ers a boost since being acquired from the Denver Broncos.

Seattle’s injury situation has Vegas favoring the 49ers, and rightfully so given the number of injuries to Seattle’s most-significant performers.

The 49ers are road 3.5-point favorites on DraftKings (-113), FanDuel (-105), and SugarHouse (-113). William Hill lists the Niners as 3-point favorites (-125).

San Francisco is 9-5-1 against the spread this year, although just 3-5-1 as favorites. Some cause for reluctance: The 49ers are 0-2 ATS as road favorites, failing to cover in wins against the Redskins and Cardinals.

The Seahawks are 7-7-1 against the spread, and 3-1 as underdogs. This is their first home game in which they weren’t favored. Overall, they’re 2-5 ATS at home this year.

The injuries throw a major curveball into this matchup. Some teams can withstand specific injuries, but Seattle is a run-heavy team and have the third-most rushing attempts in the NFL. Turbin hasn’t carried the ball since 2018, when he had just four carries for the Colts, and Lynch also hasn’t carried the ball since last year, when he had 90 rushes for the Raiders.

49ers-Seahawks Moneyline Betting

The 49ers range from -168 (FanDuel ) to -195 (SugarHouse). If you believe the Seahakws can pull off the upset, there’s good value, with DraftKings offering +163 and SugarHouse at +160.

The Seahawks have rewarded bettors as moneyline underdogs this year. They are 3-1 outright as dogs, but their injury situation makes this matchup different than their past four as dogs.

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The 49ers are 7-2 outright when favored, 2-0 outright as road favorites. Seattle was one of the two teams that beat a favored San Francisco this season but the Seahawks were much healthier for that game.

49ers-Seahawks Bears Over/Under Betting

The earlier showdown between these teams produced 51 total points but Vegas isn’t anticipating another barnburner. DraftKings, FanDuel, SugarHouse and William Hill each list the total at 47.

Seattle games this year have hit the Over and Under almost evenly, with eight hitting the Over and seven hitting the Under. Eight games involving the Seahawks have exceeded 47 points.

San Francisco is also even on the total, with seven Over and seven Under. Nine games involving the 49ers have exceeded 47 points.

Sunday Night Football Betting Preview: 49ers At Seahawks 2
Linebacker Bobby Wagner was selected to his sixth Pro Bowl. He is second in the NFL with 139 tackles.

49ers-Seahawks Notable Prop Bets

  • Away Team Win 1-6 (+375)
  • Away Team Win 7-12 (+600)
  • First to Score-Seattle (+105)
  • First Score-San Francisco TD (+170)
  • Score First/Win-San Francisco (+130)
  • Score First/Lose-Seattle (+280)

About the Author

Geoff Mosher for Bookies.com
Geoff Mosher
Geoff Mosher writes about the Eagles, 76ers and the NFL for Bookies.com. He is an award-winning sports reporter and radio and TV personality with over 25 seasons.