Week 13 of the NFL betting season serves up the traditional Thanksgiving fare, along with the latest tradition – a Black Friday affair. 

The week begins with an OG NFL matchup between the Chicago Bears and host Detroit Lions. The Cowboys and Giants meet in the annual Turkey Day game at Dallas. Thursday night, the Dolphins visit the Packers on the chilled tundra of Lambeau Field. 

The Chiefs go shopping on (Silver and) Black Friday for victory over the Raiders. 

RELATED: Super Bowl 59 Odds

The national game of the week on Sunday gives us a peek at a possible Super Bowl preview. The Philadelphia Eagles visit the Baltimore Ravens (4:25 p.m. on CBS). 

San Francisco tries to stay alive in the NFL playoff race but has to beat the Bills in Buffalo to do so. Monday night, the Browns come off a mini-bye and their magical win in the snow to visit the Denver Broncos. 

There are no teams on the bye this week. 

2024 NFL Thanksgiving Week Picks

Now it’s on to our Thanksgiving Week  NFL picks to back on your favorite sports betting app. 

2024 NFL Thanksgiving Week Best Bets 

Thursday, November 28
Chicago Bears at Detroit Lions. 12:30 p.m. (CBS)

Buzz: The Lions are playing for home-field and a first-round bye in the NFC. The crowd at Ford Field is ready to pass the stuffing – but not before Dan Campbell and the Lions roar against their OG NFL rivals. The Lions have demolished inferior teams both straight up and on the line. Detroit has covered both double-digit lines it faced this season with ease. The Bears lack any offensive recipe to keep up with the Lions. And Campbell has long demonstrated that he coaches his team to play the full 60 minutes. And leave room for dessert. 

Best Bet: Lions -10.5 (-110) DraftKings

New York Giants at Dallas Cowboys. 4:30 p.m. (FOX)

Buzz: The loser gets Bill Belichick. But does Bill Belichick want the loser? Thankfully – befitting of the day – this game kicks off at 4:30 p.m. EDT. That means most folks in the Eastern and Central Time Zones would have already eaten their holiday dinner. Let the tryptophan flow. It’s nap time. The rest of the nation may lose its appetite for football – and turkey – by halftime. Both the Giants and Cowboys have tapped out on this season. Daniel Jones and Dak Prescott are out. Tommy “Turkey” Cutlets and Cooper Rush are in. The Cowboys are winless at Jerry World this season. Why stop now? 

Best Bet: Giants +2.5 (-110) DraftKings

Miami Dolphins at Green Bay Packers. 8:20 p.m. (NBC)

Buzz: After the nearly indigestible NFL afternoon menu, we get a tasty offering for dessert. A team from South Florida visited Northern Wisconsin on Thanksgiving night. The skies will be clear, but temperatures are expected to fall into the 20s. We need the Las Vegas SuperBook or Circa to give us a number of shirt-less, inebriated Packers fans shown during the NBC telecast. The Packers have missed on 4 straight covers ahead of their game against the 49ers. The Dolphins may be aquatic creatures, but they're also warm-blooded mammals. 

Best Bet: Miami +3.5 (-110) DraftKings

Friday, November 29
Las Vegas Raiders at Kansas City Chiefs. 3 p.m. (Amazon Prime)

Buzz: Call it Silver and Black Friday on Amazon Prime. The Raiders visit Kansas City in what has become a new NFL holiday tradition – along with Christmas games buffering, er streaming, on Netflix. The 9-1 Chiefs took their loss in Week 11 on the road at Buffalo. But they’ve endured plenty of scares, including that 16-14 win over the Broncos thanks to a blocked field goal at the gun. Seven of KC’s first 9 wins were by less than one score. KC was just 5-5 on the line through 10 games. Meanwhile, the Raiders, despite being 2-8, trailed the Chiefs by just one game ATS. The real challenge for the Raiders will be scoring. But these teams have gone over in 6 of 7 games ahead of Week 12.

Best Bet: Over 43.5 Points (-110) DraftKings

Sunday, December 1
Seattle Seahawks at New York Jets, 1 p.m. (FOX)

Buzz: Speaking of leftover turkeys, the Jets play host to another one of their former quarterbacks this week in Geno Smith. The veteran QB played his first 4 seasons for Gang Green. Smith is well aware of what awaits in the chill and wind swirls of Northern New Jersey. The Jets have failed to cover 6 straight times against NFC opponents and continue their decade-plus tailspin this season. They sit 3-8 SU and ATS coming off the bye and dismissal of GM Joe Douglas. Aaron Rodgers is like that guy in the famous “Twilight Zone” episode who dies and gets everything he wants. Only then does he realize he’s not in heaven. But that other place. The Seahawks are in the middle of the race for the NFC West – and one of the last playoff berths in the NFC.   

Best Bet: Seahawks +1.5 (-110) DraftKings

Los Angeles Chargers at Atlanta Falcons, 1 p.m. (CBS)

Buzz: The Falcons don’t seem like a team that wants to win the NFC South, despite having the opportunity to distance themselves from the pack. Atlanta entered the bye coming off consecutive losses to the Saints (20-17) and Broncos (38-6). The Chargers’ defense adds some needed juice to Jim Harbaugh’s team and takes much of the burden off Justin Herbert's offense. The Bolts boast the No. 1 scoring defense in the NFL, giving up just 14.5 PPG. The Falcons have failed to cover in 7 straight games against AFC opponents.  

Best Bet: Chargers -1.5 (-110) DraftKings

Pittsburgh Steelers at Cincinnati Bengals, 1 p.m. (CBS)

Buzz: The Steelers (8-3) come off the mini-bye after being left in the snowbank by Jameis Winston and the Browns. This AFC North matchup doesn’t carry nearly as much hate as the one between Pittsburgh and Cleveland. The Bengals (4-7) continue their slow and painful disintegration. They entered their bye coming off a one-point loss to the Ravens and a one-score loss to the Chargers. Cincy blew a 21-point lead in the second half in their loss to LA. The Steelers have covered in a tied-for-NFL-best 8 games this season.  

Best Bet: Line TBD DraftKings

Arizona Cardinals at Minnesota Vikings, 1 p.m. (FOX)

Buzz: Bettors have enjoyed a solid return backing the Cardinals and Vikings this season. Each team went 7-3 ATS in its first 10 games. The Cardinals have been enjoying a solid heater of late, winning SU and ATS in their past 4 games ahead of their NFC West clash in Seattle. But the Cardinals haven’t been able to get airborne in Minnesota. They’ve lost 11 straight to the Vikings on the road. But we don’t like this number in a game that could well be decided on a last-second kick. The Cardinals have a strong running game this time, but the Vikings are tops in the NFL against the run. Lean into the under on this one. 

Best Bet: Under 47 Points (-110) DraftKings

Indianapolis Colts at New England Patriots, 1 p.m. (CBS)

Buzz: The Colts were tied with the most wins ATS (8) in the NFL this season ahead of their game against Detroit in Week 12.  A year ago, the Patriots imploded in a loss 10-6 to the Colts in Munich. Turns out, that game sealed the fate of Bill Belichick and QB Mac Jones. This season, the Patriots have a new coach and a new QB. This might finally be the game in which Drake Maye is given the keys to the Patriots’ offense that he earned weeks ago. 

Best Bet: Patriots +2.5 (-110) DraftKings

Tennessee Titans at Washington Commanders, 1 p.m. (CBS)

Buzz: Remember the Titans? Bettors backing Tennessee can’t wait to forget 2024. The Titans were an NFL-worst 1-9 on the line through their first 10 games. The Commanders hit a pair of potholes with back-to-back losses against Pittsburgh and Philly. They get the Cowboys this week. They’re in the middle of the NFC Wildcard race. The Titans have the best-passing defense in the NFL, but the 29^th most potent offense. The difference here will be Washington’s running game and its defensive front. 

Best Bet: Commanders -7 (-110) DraftKings

Houston Texans at Jacksonville Jaguars, 1 p.m. (FOX)

Buzz: A cool and clear late fall afternoon greets the visiting Texans. Ideal weather for football. The Jaguars come off the bye at a respectable 6-5 ATS. But they’re just 2-9 ATS and have lost 4 straight. And gave up an embarrassing 52 points to Detroit. The Texans are on the way to another AFC South title. They ended a 2-game losing streak with an easy win over Dallas. This number is a bit wobbly, given how the Jaguars might show up at home. Jacksonville is anemic enough on offense to keep this total on the under.

Best Bet: Under 42.5 Points (-110) DraftKings

Los Angeles Rams at New Orleans Saints, 4:05 p.m. (FOX)

Buzz: Two underperforming teams play in the background on Sunday Ticket while you’re shopping on your phone. The Saints are coming off the bye and back-to-back wins over the Falcons and Browns. The Rams won 4 of 5 ahead of their game against the Eagles. That run put them in the race for the mediocre NFC West. Matthew Stafford in a dome is always a tough out. Especially up against what will be an overmatched New Orleans secondary. Give the points here, or shop around for a decent price on the Rams moneyline. 

Best Bet: Rams -2.5 (-110) DraftKings

Tampa Bay Buccaneers at Carolina Panthers, 4:05 p.m. (FOX)

Buzz: The Panthers' defense ranks last in points allowed and rushing yards. And that was before it faced Patrick Mahomes and the Chiefs. Baker Mayfield and the Bucs can score, especially against softer defenses. Tampa Bay has been depleted by injuries. While Chris Godwin is lost for the regular season, Mike Evans should definitely be back in full form by this game. The Bucs running game will also find its footing in Charlotte.

Best Bet: Buccaneers -6.5 (-110) DraftKings

Philadelphia Eagles at Baltimore Ravens, 4:25 p.m. (CBS)

Buzz: A potential Super Bowl 59 preview tops the marquee this week. The Eagles are steadily reaching altitude after a choppy start. Philly won 6 straight heading into SoFi Stadium this week. Philly has held its own ATS, covering in 6 of its first 10 games. Baltimore has underperformed on the line, going 5-5-1 ATS and 7-4 SU. The Ravens have covered in 4 of their first 5 games when giving 4 or fewer points. The Eagles' defense matches up well against Baltimore’s passing and rushing game. Or as well as one can against Lamar Jackson and Derrick Henry. The same holds when the Eagles look to run. The weakness continues to be in Baltimore’s secondary. An interception-free performance from Jalen Hurts can deliver the win and cover here. 

Best Bet: Eagles +3 (-110) DraftKings

San Francisco 49ers at Buffalo Bills, 8:20 p.m. (NBC)

Buzz: The 49ers (5-5 ahead of their game at Green Bay) have been flirting with disaster in true “Molly Hatchet” form. They lost to the Chiefs (no shame there). They beat the woeful Cowboys by 6 points. They almost lost at Tampa Bay. And got clipped by the Seahawks 20-17 at home. Brock Purdy is not ready for a night game in Orchard Park. Josh Allen may have clinched MVP honors with his game-winning dash against the Chiefs. The Bills are making what will be a last run for the Super Bowl with this bunch. 

Best Bet: Bills -3 (-110) DraftKings

Monday, December 2
Cleveland Browns at Denver Broncos, 8:15 p.m. (ESPN)

Buzz: The Browns won their Super Bowl in the snow against Pittsburgh. They come to Denver off the mini-bye. There won’t be any adverse conditions this time weather-wise. The Broncos are tied for the most wins ATS (8) in the NFL after 11 games. This will be their second week giving 6 points. Their biggest number of the season (-13.5 points) ended with a win and covered 28-14 against Carolina. 

Best Bet: TBD DraftKings