The NFL Playoffs kick off Saturday with two AFC wild-card showdowns. Deshaun Watson and the AFC South champion Houston Texans host Josh Allen and the upstart Buffalo Bills, then Tom Brady and the defending Super Bowl champion New England Patriots host NFL rushing leader Derrick Henry and the Tennessee Titans.

Let’s take a look at some of the best bets fans of NFL betting should consider:

Bills-Texans Best Bets

OTHER BETS TO BACK

• First Half | Under 19.5 Points +115 (BetMGM)
• Score First And Lose | Texans +370 (FanDuel)

All odds current as of publication but subject to change. Check out the latest Bills-Texans odds here.

PICK 1: Bills +3

Buffalo is the NFL’s best road-covering team, Houston is the worst home-covering team still playing. Buffalo’s top defensive strength is stopping wideouts — just six TDs in 16 games — and if it can limit DeAndre Hopkins, Buffalo has a real shot at winning and advancing. Josh Allen and Devin Singletary should find opportunities against Houston’s porous defense.

PICK 2: First Half — Under 19.5 Points

These teams combined all season to average exactly 19.5 first-half points per game. But they’ve allowed only 18.7 and that number the last three weeks has dropped to 15.6 (their first-half scoring has dipped as well lately). Each offense will take time adjusting to the defenses.

PICK 3: Score First and Lose — Texans

Houston has scored the opening TD in three straight games and in five of eight overall. Eventually I like Buffalo to not only cover but to win, but don’t be surprised if the amped-up home team draws first blood.

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Titans-Patriots Best Bets

OTHER BETS TO BACK

• First Score | Patriots TD +170 (FanDuel)
• James White and Derrick Henry TDs | +400 (William Hill)

All odds current as of publication but subject to change. Check out the latest Titans-Patriots odds here.

PICK 1: Titans +5

The Titans are averaging 33.4 ppg the last seven weeks and are 7-3 with Ryan Tannehill under center. They have the NFL’s rushing leader in Derrick Henry, too. New England’s defense will likely keep Tennessee’s scoring lower than usual, but the Patriots’ offense is averaging just 21 ppg the second half of the year. Mike Vrabel gets up for playing the Pats and it showed last year in a Tennessee rout.

CHECK OUT: Bookies.com NFL Week 17 Betting Power Rankings

PICK 2: First Score — Patriots TD

No team averages more first-quarter points than the Patriots, and prior to their two-game slipup to end the season, they’d scored first in four in a row, three of those times were TDs. The Titans have been notoriously slow out of the gate. The opponent has scored first in four of the last five, and all were of the six-point variety.

James White and Derrick Henry TDs

Derrick Henry will get the ball early and often — he carried it 32 times against the Patriots last year — and if the Pats defense has a weakness, it’s against the run. Meanwhile, the Titans rank 31st in defending pass-catching RBs, a perfect situation for James White, who has four TDs the last five games, all on receptions.

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