Adam Thompson for

By Adam Thompson | | 5 mins

MLB Playoffs Odds & Picks: Complete ALDS & NLDS Predictions

MLB Playoffs Odds & Picks: Complete ALDS & NLDS Predictions

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The frenetic best-of-3 MLB wild-card round produced more than a few dramatic moments. Now it’s back to business for the remaining teams, with the MLB Divisional Series gearing up for the remaining eight.

The best-of-5 ALDS starts on Monday at neutral sites. The Rays and Yankees face off in San Diego, while the Athletics and Astros meet in Los Angeles. The National League series begin Tuesday in Texas, and we are still awaiting those matchups.

Here are the latest MLB odds for every series and how we see them shaking out.

CHECK OUT & BOOKMARK: Daily Expert MLB Picks Throughout The Playoffs

ALDS Odds & Picks

Rays vs Yankees

Odds: Yankees -148, Rays +120

The Rays are the No. 1 seed in the American League. The Yankees were the preseason favorites to win the AL pennant before injuries crushed their depth and they finished No. 5. The Yankees, however, are the big favorites here.

But Tampa went 8-2 in the season series, and only two of those wins were by one run. Rays pitchers kept the vaunted Yankees bats to just 3.4 runs per game and may benefit further against the HR-dependent Yankees with these games held at pitcher-friendly Petco Park in San Diego.

The Yankees should get Gerrit Cole for Games 1 and 5, which offers an advantage. But New York absolutely must win the opener and hope there is a deciding fifth game. Cole went 0-1 with a 4.96 ERA in three starts vs. Tampa in 2020. PICK: RAYS IN 4

Astros vs Athletics

Odds: A’s -118; Astros -104

Stats-wise, the A’s and Astros have a lot of similarities – with the bats. But Oakland’s pitching was far superior, both in the starting rotation and in the bullpen, and it showed throughout the season and when these teams played each another. Oakland beat Houston in seven of 10 meetings. In all seven A’s wins the Astros were held to two runs or less.

Houston’s offense has trended downward in the last month, too, averaging just 3.8 rpg in September. Oakland’s bats were only slightly better, but if its pitching does what it’s done all year, the A’s move on. PICK: ATHLETICS IN 4

Odds to Win The American League


Odds via DraftKings and current as of publication; check out live AL pennant odds here


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NLDS Odds & Picks

Braves vs Marlins

Odds: Braves -286, Marlins +225

The Braves ranked second in MLB in average, runs scored and homers hit. From top to bottom any spot in the order can produce, and the mix of size, strength, side of the plate and speed make it a challenge for pitchers to handle the diversity of the lineup.

Atlanta’s pitching staff finished middle of the pack, but it was top-heavy. That was showcased in a pair of shutout wins over the Reds in the NL wild-card round.

If one wonders how the Marlins got this far, it’s fair. They finished in the bottom half of just about every offensive category and 21st in pitching. They went 31-29 but were outscored by 41 runs on the year – 24 runs worse than any other team in the postseason.

Miami got a favorable draw against a slumping and overrated Cubs squad, and took advantage. Atlanta offers a far stronger challenge. PICK: BRAVES IN 3

Dodgers vs Padres

Odds: Dodgers -286, Padres +225

The Padres’ bats were awesome this year, guiding San Diego to one of its best seasons in recent memory. But as good as they were, the Dodgers were better offensively in nearly every facet.

Los Angeles ranks No. 1 in runs scored and home runs while also having MLB’s best ERA. It’s a wet-blanket scenario for the Padres, who are top-10 at the plate and on the mound but lost the season series with the Dodgers.

Another Padres bummer: Top pitchers Dinelson Lamet and Mike Clevinger sat out in the wild-card round and are questionable for the NLDS. If they don’t play, San Diego’s chances drop from unlikely to highly unlikely. PICK: DODGERS IN 4

Odds to Win The National League


Odds via BetMGM are current as of publication; check out live NL pennant odds here


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COMPARE: The Latest World Series Odds From Top Sportsbooks

Adam Thompson’s MLB Playoffs Betting Recap

AL Wild-Card Picks: Rays (-210) over Blue Jays, White Sox (+110) over A’s, Twins (-120) over Astros, Yankees (-135) over Indians. Record: 2-2 (-20)

NL Wild-Card Picks: Dodgers (-300) over Brewers, Reds (+105) over Braves, Marlins (+160) over Cubs, Padres (-175) over Cardinals. Record: 3-1 (+260)

About the Author

Adam Thompson for
Adam Thompson

NFL writer and expert Adam Thompson joined in 2019 after a successful run as senior handicapper for SportsLine and He has consistently produced profitable seasons in NFL and college football and established himself as an elite MLB expert in 2018, hitting 61 percent of his money line picks for a profit of $4,062 to $100 players, ending the season on a 22-4 run including 100 percent on World Series games. Previously the award-winning sports editor of the Green Bay Press-Gazette, Adam spent nearly 20 years covering the NFL, MLB and college football. Now he shares the insight he gained at through well-reasoned picks and thought-provoking articles and on Twitter at @_Adam_Thompson_.