Buccaneers vs. Lions Odds, Best Bets & Player Props For MNF NFL Week 7

By Adam Thompson Oct 20th, 2025 11:35 AM EDT

NFC powerhouses face off in a big Monday Night Football matchup, as Jared Goff and the Detroit Lions host Baker Mayfield and the Tampa Bay Buccaneers.

The Lions (4-2) look to bounce back after a loss to the Chiefs in Week 7. The Buccaneers (5-1) have won two straight despite injuries taking out several top performers.

The latest Buccaneers vs. Lions NFL Odds has Detroit at -6, up from -5.5 for most of the week. The Over/Under for total points is at 53.5 at the best sports betting sites.

Bookies.com veteran NFL handicapper Adam Thompson – who has hit on a whopping 60.2% of his NFL picks five years running, reveals his plays for this MNF showdown.

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Buccaneers vs. Lions Betting Predictions

Buccaneers vs. Lions Point Spread

Injuries to the Lions defense were exposed in a 30-17 loss to the Chiefs in Week 6. Many of those issues, especially in the defensive backfield, are going to be an issue here against an often-prolific Bucs offense.

The Lions are going to score as well, likely mostly through the air with Tampa’s elite run defense forcing a more one-dimensional attack. We’ll take the points with the Buccaneers and a backdoor cover definitely in play.

Buccaneers vs. Lions Over/Under

These teams average a combined 59.3 ppg – nearly six points above the posted total. That line is betting us to take the Over on Monday night.

We won’t take the bait. Tampa’s defense can take away Detroit’s run, and a pass-heavy Lions attack isn’t as effective. Conversely, the Bucs will be without Bucky Irving, Chris Godwin and perhaps Emeka Egbuka. We expect a close game, but not a high-scoring one. Back the Under as a secondary play.

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Buccaneers vs. Lions Same Game Parlay

1. Jared Goff, Over 261.5 Pass Yards (-110): The Lions QB has exceeded 260 yards just once all season, against the porous Bengals. But Tampa Bay’s top defensive focus has been slowing the run, and it’s been very successful at it. The Bucs have allowed 341 and 296 pass yards the last two weeks.

2. Baker Mayfield, Over 1.5 TDs (-172): Mayfield should have Mike Evans for this one; that might be it for the regulars, but he’s still thrown two-plus TDs in five of six games. The Lions allow 2.2 pass TDs per game, fifth-most.

3. Buccaneers +6 (-110): We’re expecting a close-enough game – close enough that Mayfield can make a fourth-quarter run and keep it within a TD.

Same Game Parlay Odds: +476

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