Two of the great QBs of all time face off against two of the franchises they've horrified for roughly two decades in Week 14. Tom Brady leads the Tampa Bay Buccaneers against the Buffalo Bills, while Aaron Rodgers guides the Green Bay Packers against the rival Chicago Bears on Sunday night.

Brady, who tormented the Bills for 20 years when he was with New England, has won 32 of 35 games against them. Obviously his Patriots were the favorite in nearly all those games, but Brady is also 22-12-1 (64.7%) against NFL spreads vs. Buffalo.

Rodgers has crushed the Bears for nearly two decades, with a lifetime record of 21-5 vs. the NFC North foe, with 57 TDs and 6,208 yards (and just 10 INTs). Like Brady’s Patriots, Rodgers’ Packers have usually been favored on betting apps in these matchups, but Rodgers is 19-7 ATS (73.1%) vs. Chicago as well.

Bookies.com NFL handicapper Adam Thompson has now hit on 60% of his best bets in the 2021 NFL season, and over 60% each of the last three seasons. Here are his five best bets at sportsbooks and betting sites for Week 14:

RELATED: NFL Week 14 Odds & Betting Lines For Every Game

NFL Sunday Week 14 Best Bets

Broncos ATS over Lions

Detroit finally got its first win and has been playing better lately - defensively. Against a Broncos team that has held the offenses of the Chiefs, Chargers and Cowboys to 15 points or less over the last four games, don’t expect anything more than 13-16 points. Denver needs to get out of its own way offensively, and this is a good opponent to bounce back. (Locked in at -7.5 at bet365)

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Saints ATS over Jets

This is Taysom Hill’s team now, and while Game 1 didn’t go well – four INTs – the defense has been playing good enough and Alvin Kamara should be back. The Jets, meanwhile, rank 30th in NFL vs. both the pass and the run, and in rushing. They’ll throw the ball, but turnover prone QB Zach Wilson faces a defense with the fourth-most INTs. (Locked in at -5.5 at SugarHouse)

Browns ATS over Ravens

The Browns had their bye week to stew over a 16-10 loss to the Ravens two weeks ago, one in which the Chubb-Hunt Express went for just 15 carries for 36 yards. The bye week came at a perfect time for the banged-up Browns, who picked off Lamar Jackson four times.

Baker Mayfield really needs a performance, but he owns four 340-yard pass games in seven all-time meetings with Baltimore. The Ravens have allowed more pass yards than any team. If Baker can’t lead the way here, a change might be in store for 2022. (Locked in at -2 at BetMGM)

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Giants ATS over Chargers

Here's one for New York sports betting fans to back: The Giants are 3-3 their last six games with only one of the losses by more than Sunday’s spread (and that was vs. the Buccaneers). Jake Fromm may get his first-ever NFL action and that’s not great, but the pass game wasn’t a factor anyway. The Chargers’ run defense allows over 141 ypg, so it’s time for Saquon Barkley to do his thing.

The Giants’ personnel and strengths on defense may match up well with Justin Herbert. The Chargers make headlines, but they’re only 4-4 the last eight games, and only one of those four wins was by more than five points. (Locked in at +10.5 at DraftKings)

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RELATED: NFL Week 14 Picks & Best Bets For Every Game

Titans ATS over Jaguars

It’s OK to have some concern in backing a Titans team that lost its identity when Derrick Henry was lost for the season, lost two straight and are on a 0-3 ATS dip. But this is the Jaguars. Teams that play Jacksonville get back on track. The Jags are averaging under 11 ppg the last six weeks and have allowed 30-plus in half those games. The Jaguars are winless on the road with the losses by an average of 15.8 ppg. (Locked in at -8.5 at bet365)

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