The Buffalo Bills are a Super Bowl contender right now. What they do at the 2022 NFL Draft could push them into favored status.

Buffalo is coming off an 11-5 season, one in which it ranked top five in offense for the second year in a row. Its defense, which ranked 16th in points allowed and 14th in yards allowed in 2020, ranked as the very best in both instances in 2021.

Buffalo is available around +750 to win Super Bowl 57 on NFL futures markets, right there with the Buccaneers and Chiefs atop most tables. Following the launch of Ontario sports betting, Bills fans north of the border finally have the opportunity to wager on their NFL team. The right draft picks over the final week of April could put Buffalo over the top.

Bookies.com oddsmaker Adam Thompson has revealed who the Bills are most likely to choose with the No. 25 overall pick in the 2022 NFL Draft.

Buffalo Bills 1st Round Pick Odds (No. 25)

Odds are projected and do not reflect any odds that may be available at legal betting sites or betting apps.

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Who Will The Bills Take In The NFL Draft?

The Bills don’t have any glaring issues, but the defense was a modest 13th vs. the run, while the offense won't have Cole Beasley (cut) and Emmanuel Sanders (not resigned) in 2022. They added LB Von Miller in a huge free agent addition. A top-level cornerback isn’t out of the question, though the chief focus likely turns to keeping up with the elite offenses of the AFC.

Devin Singletary has shown the potential to be an RB1 for Buffalo, but only one running back is considered a possible first-rounder (Iowa State’s Breece Hall), and he's a fringe first-rounder at that. Depth on both lines remains a need, especially on the interior. If offensive guard Zion Johnson is there, that might be tough to pass up. The same goes for Georgia DT Devonte Wyatt.

RELATED: Tampa Bay Buccaneers NFL Draft Odds: Offensive Line Needs Help

Andrew Booth Jr. Odds To Join The Buffalo Bills

While a shiny new wideout or a hulking interior lineman would be nice, cornerback is an important area of need (Tre'Davious White is coming off a torn ACL and Levi Wallace left in free agency), and there should be at least one immediate-impact CB at No. 25. Clemson’s Andrew Booth Jr. and Washington’s Trent McDuffie highlights the possibilities.

While McDuffie was a shutdown corner for the Huskies, his slight frame give NFL scouts question as to whether his game can translate as well in the NFL. That’s not the case with Booth Jr., whose size (6-foot, 190) and physicality are conducive to both zone and man styles.

Complete List of Bills 2022 Draft Picks

• Round 1 (Pick 25)
• Round 2 (Pick 57)
• Round 3 (Pick 89)
• Round 4 (Pick 130)
• Round 5 (Pick 168)
• Round 6 (Pick 185 from CAR)
• Round 6 (Pick 203)
• Round 7 (Pick 231 from ATL)

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