Best NFL Week 2 Betting Tips: How to Bet On the NFL In The UK

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NFL fans in the UK can get ready to lose their Thursdays, Sundays and Mondays for a few months, as the 2025 season is here! With so many games each week, it can be easy to get lost when looking to place a bet on the NFL at top UK betting sites. That's why we have put together our experts' NFL betting tips to point you in the right direction.

We've got you covered with our NFL best bets, NFL bet builders, NFL acca tips and NFL player prop tips, with the best odds from UK betting sites. Keep reading for our best NFL betting tips for this week's action.

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Best NFL Week 2 Betting Tips

NFL TipOddsBookmaker
Bills Over 30.5 Points5/4Spreadex
Patriots ML, 49ers ML, Cardinals ML, Eagles ML6.32/1Betfred
Gibbs anytime TD, Goff Over 1.5 Passing TDs, Over 46.5 Points, Lions -6.522/5bet365
AJ Brown 100+ Receiving Yards3/1bet365
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NFL Best Bets

Call it whatever you like - the NAP, the lock of the week, this week's banker. Every week, we'll pick out our best bet in the NFL. While our other selections will have juicier prices, our best bet will be the selection we're most confident in. With hundreds of markets to choose from at NFL betting sites, you'll be spoilt for choice. If you're having one bet on the NFL this week, this is what we would advise it should be.

Best NFL Betting Tip for Week 2

The Buffalo Bills and Baltimore Ravens auditioned for game of the season in Week 1, when Josh Allen and Co. came back from 15 points down with fewer than 12 minutes remaining Monday night to win 41-40.

The New York Jets looked to have a little bit of life in their offense but were put to the sword defensively by the limited 41-year-old Aaron Rodgers. If he can efficiently put up four touchdowns against the Jets, imagine what Allen might do. The second meeting between these two last season saw the Bills score 40, and we could see something similar this week.

Back Bills Over 30.5 Team Points at 5/4 with Spreadex

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NFL Acca Tips

In any given week, there can be up to 16 games taking place in the NFL. That's a lot to get your head around at new betting sites. Every week, our team of experts will pick the best NFL acca tips. Most punters choose to do their NFL accas on moneyline, handicap and total points markets, but there's no limit to what you can choose. We advise choosing an acca insurance site to give yourself a chance of getting your stake back as a free bet if only one selection lets you down.

Best NFL Acca Tip - Week 2

It’s tough to draw conclusions after one week of the season, but there’s real cause for concern for some NFL teams. The Dolphins and Panthers really stood out as two teams that are likely to struggle this season and are both fancied to add another L in Week 2. 

The 49ers overcame major injury woes to get past the Seahawks and should have far too much for the Saints to handle, even with their depleted offense. 

The game of the week looks to be the Eagles - Chiefs matchup. The Eagles arrive fresh off a big divisional win, while the Chiefs had a long trip home from Brazil following their losing effort against the Chargers. We fancy Jalen Hurts and co. to get off to a 2-0 start. 

Patriots, 49ers, Cardinals and Eagles to win at 6.32/1 with Betfred

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NFL Bet Builder Tips

The NFL is always something to look out for when browsing the best bet builder sites. A lot of lines on NFL games are priced up as pick 'ems, which isn't much use for punters looking to back something at a bigger price. With NFL bet builders, you can combine multiple selections from a range of markets on the same game and combine them into one bet. Check out our best NFL bet builder tip below.

Best NFL Bet Builder Tip - Week 2

The Lions weren’t able to get much done on offence in week one against the Packers, but the Packers might be the team to beat this season so the Lions can’t be written off just yet. Back in a dome their speedy offence will be better suited to conditions and should be able to rack up points against a Bears team whose defence won’t offer anywhere near as much resistance to the Lions passing attack.

Gibbs anytime TD, Goff Over 1.5 Passing TDs, Over 46.5 Points, Lions -6.5 at 22/5 with bet365

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Best NFL Player Prop Bets

Player props have become one of the most popular NFL markets on betting apps. With these, you can back players to have over or under a set amount of yards, receptions, rushing attempts, tackles, sacks, interceptions or anything else you can think of. Some bookies on our list of betting sites also have player milestone betting, which offers higher lines and bigger odds as a result. Here's this week's best NFL player prop bet:

Best NFL Player Prop Tip - Week 2

Philadelphia receivers weren’t called on much last week as the Eagles squeezed past the Cowboys in the season opener, with Jalen Hurts recording just 152 passing yards, but all that could change this week in a blockbuster Super Bowl rematch as the reigning champions head to Kansas City.

The Chiefs are 0-1 after losing 27-21 to the Los Angeles Chargers in Brazil last week, giving up 318 yards and three touchdowns through the air. If the Eagles plan to be more balanced this week, then the man with five 1,000-yard seasons in his career should be able to feast.

Back AJ Brown 100+ receiving yards at 3/1 with bet365

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How to Bet on the NFL - Week 2

Our aim at Bookies.com is to give you everything you need in one place for betting on the NFL. On this page, we've provided our best NFL betting tips for the week, along with a list of new customer betting offers from top UK sites.

Once you have chosen your preferred betting site, click on the link on this page to be brought to the site. Doing this will link the welcome offer to your new account. Next, sign up by entering your details on the betting site, select a payment method and make your first deposit.

To place a bet, choose American football from the list of sports available. Go to the game you want to bet on and click on the odds beside your chosen selection. This will add it to a betslip, which will appear on the page. Enter your stake, confirm the bet and voila. All that's left to do is cheer your selection on and hopefully watch it win. Once your qualifying bet settles, you'll be eligible to receive any free bets that were part of the welcome offer.

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