Best NFL Betting Tips: How to Bet On the NFL In The UK in Week 5

By Mark Fordham Oct 3rd, 2025 9:17 AM EDT

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NFL fans in the UK can get ready to lose their Thursdays, Sundays and Mondays for a few months, as the 2025 season is here! With so many games each week, it can be easy to get lost when looking to place a bet on the NFL at top UK betting sites. That's why we have put together our experts' NFL betting tips to point you in the right direction.

We've got you covered with our NFL best bets, NFL bet builders, NFL acca tips and NFL player prop tips, with the best odds from UK betting sites. Keep reading for our best NFL betting tips for this week's action.

Best NFL Week 5 Betting Tips

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NFL Best Bets

Call it whatever you like - the NAP, the lock of the week, this week's banker. Every week, we'll pick out our best bet in the NFL. While our other selections will have juicier prices, our best bet will be the selection we're most confident in. With hundreds of markets to choose from at NFL betting sites, you'll be spoilt for choice. If you're having one bet on the NFL this week, this is what we would advise it should be.

Best NFL Betting Tip for Week 5

Dallas Cowboys have been one of the most fun teams to watch this season with 114 points to their name in just four games, including 40-point outings against New York Giants and Green Bay Packers. Even if CeeDee Lamb misses this weekend, George Pickens is coming off a hat-trick against the Packers, and no team is putting up more yards per game than the Cowboys this season.

New York Jets, meanwhile, have been absolutely dire defensively with 120 points against, conceding 27 or more in each game, and they surely stand little chance of bucking that trend against the potent Dallas attack.

Back Cowboys over 27.5 points against the Giants at 29/20 with Ladbrokes

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NFL Acca Tips

In any given week, there can be up to 16 games taking place in the NFL. That's a lot to get your head around at new betting sites. Every week, our team of experts will pick the best NFL acca tips. Most punters choose to do their NFL accas on moneyline, handicap and total points markets, but there's no limit to what you can choose. We advise choosing an acca insurance site to give yourself a chance of getting your stake back as a free bet if only one selection lets you down.

Best NFL Acca Tip - Week 5

The Colts continue to surprise even when falling to their first loss of the season. They had more than enough opportunities to win the game against the Rams. When your wide receiver drops the ball before breaking the goal line and then you try to defend a deep ball with only 10 defenders on the field, it’s fair to think you might have shot yourself in the foot losing by only three. The same Colts should have no trouble with the Raiders.

The Saints are 0-4 and have rockstar rookie Jaxson Dart breathing life into the Giants coming to town. But with the benefit of a week’s worth of game tape, the plucky Saints could bring the quarterback back down to Earth. The Saints have been in most of the games they have played; if they can finish this one, they can win.

Not convinced we have seen what the Eagles truly are this year. For quarters they can be unbelievably bad and other quarters they look like the defending Super Bowl champions they are. The Broncos have been a little disappointing thus far, and that could continue here.

The Chargers were stunned by the Giants in Week 4, but with so many players not making the game for the Commanders, this should be an easy W for Justin Herbert and Co. even with Jayden Daniels returning.

Back Colts, Saints, Eagles, Chargers to win at 5/1 with BetMGM

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Hope is here. Call (800) 327-5050 or http://gamblinghelplinema.org
Play it smart from the start! Live Chat @ http://GameSenseMA.com

NFL Bet Builder Tips

The NFL is always something to look out for when browsing the best bet builder sites. A lot of lines on NFL games are priced up as pick 'ems, which isn't much use for punters looking to back something at a bigger price. With NFL bet builders, you can combine multiple selections from a range of markets on the same game and combine them into one bet. Check out our best NFL bet builder tip below.

Best NFL Bet Builder Tip - Week 5

Isaiah Bond has seen his role in the Browns offense grow as the season has gone on, with his targets increasing from one in Week 1 to three and four, followed by six last week. With Cedric Tillman out of the picture and David Njoku banged up, Bond could be in line for even more looks from rookie QB Dillon Gabriel. 

Gabriel is also responsible for the other leg of this NFL bet builder. Sunday marks his first NFL start. Unfortunately, it comes against one of the league’s better defenses without a week at home of normal prep. Expect Jalen Redmond to pick up his fourth sack of the season against the inexperienced signal-caller.

Back Bond 4+ receptions and Redmond to record a sack at 17/2 with bet365

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Best NFL Player Prop Bets

Player props have become one of the most popular NFL markets on betting apps. With these, you can back players to have over or under a set amount of yards, receptions, rushing attempts, tackles, sacks, interceptions or anything else you can think of. Some bookies on our list of betting sites also have player milestone betting, which offers higher lines and bigger odds as a result. Here's this week's best NFL player prop bet:

Best NFL Player Prop Tip - Week 5

Much to the annoyance of AJ Brown, the Eagles offense has pretty much gone through Barkley this season. That doesn’t look like changing this weekend either when the Eagles face one of the best pass defences in football. That should result in plenty more work for Barkley both on the ground and through the air out of the backfield.

Back Saquon Barkley 125+ rushing and receiving yards at 23/10 with bet365

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How to Bet on the NFL - Week 5

Our aim at Bookies.com is to give you everything you need in one place for betting on the NFL. On this page, we've provided our best NFL betting tips for the week, along with a list of new customer betting offers from top UK sites.

Once you have chosen your preferred betting site, click on the link on this page to be brought to the site. Doing this will link the welcome offer to your new account. Next, sign up by entering your details on the betting site, select a payment method and make your first deposit.

To place a bet, choose American football from the list of sports available. Go to the game you want to bet on and click on the odds beside your chosen selection. This will add it to a betslip, which will appear on the page. Enter your stake, confirm the bet and voila. All that's left to do is cheer your selection on and hopefully watch it win. Once your qualifying bet settles, you'll be eligible to receive any free bets that were part of the welcome offer.

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21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MI, NC, NJ, OH, PA, TN, VT, VA, WV, or WY. Must sign up by 9/30/25. Apply offer in bet slip; place $1+ American football cash wager w/ odds +300 or longer each Game Day. Wager must settle as loss to qualify for FanCash equal to the amount of losing wager (up to $100 FanCash per Game Day). Rewards expire 10/31/25. Terms, including FanCash terms apply-see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA).

About the Author

Mark Fordham

More About Mark

Mark spent over a decade as a sports reporter and editor with Goal.com and Bleacher Report. He is now a Content Editor at Bookies.com covering all manner of sports from the Premier League and cricket to the NBA and NFL, and is our resident EPL tipster. Mark also has years of experience working with all things online casino, and knows a good one from a bad one.

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