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Most Bet On Week 2 NFL Games - Which Have Most Action

Bill Speros for Bookies.com

Bill Speros  | 12 mins

Most Bet On Week 2 NFL Games - Which Have Most Action

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More money was wagered on NFL betting in Week 1 of the 2021 NFL season than in any week since nationwide sports betting got the green light by the Supreme Court in 2018. Whether or not Week 2 delivers another record-breaking performance may depend on how badly newbies lost in Week 1.

Favorites went a paltry 3-13 and many of the titans (not to mention the Titans) who fell had absorbed significant amounts of handle money.


Week 2 lacks the months-long hype that preceded Week 1. If you want to see that contrast manifest itself, look no further than the Thursday night matchup. Last week, Tom Brady and the Bucs opened defense of their NFL title at home against Dak Prescott and the “Hard Knocks” Dallas Cowboys. This week, the Thursday night quarterback matchup featured Daniel Jones and Taylor Heinicke.

Week 2 NFL odds have three games with double-digit point spreads, up from none last week. There are seven home underdogs on the board, as well.

Make Some Noise

Most Bet On Week 2 NFL Games - Which Have Most Action 1

Week 1 saw NFL games played inside full stadiums for the first time since 2019. Crowd noise delivered for the home team when it came to winning outright in several upsets.

The Bengals and Raiders won at home in overtime, both pulling off outright and betting upsets in front of sellout crowds. The Lions rallied at home after being down 28 points to grab at backdoor cover at +9. The Rams stomped the Bears at SoFi Stadium, which was loud and loaded. Arrowhead Stadium in Kansas City lived up to its reputation in terms of decibels as the Chiefs rallied to beat the Browns late. Although the Browns held on for the backdoor cover.

Even the lowly Texans got a boost from those fans who showed up in Houston.

Not all home teams won. The Patriots, Titans and Bills all faltered in their stadiums as home favorites and lost outright. Bills Mafia never made it past the Causeway tollbooth.

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Major Week 2 Line Movements

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Several games have seen their lines move they were originally posted in the spring. Here’s a look at some shifts of note:

Patriots at Jets

Opening Line: Patriots -3.5

Current Line: Patriots -5.5

The Buzz: There are two mega-trends pushing this line toward New England. One is Bill Belichick’s success against rookie QBs. The other is the almost unthinkable possibility of New England falling to 0-2 in the AFC East. Bettors in New Jersey who want to tempt the Underworld Fates and back Gang Green may never get a better chance getting a touchdown and missed PAT at home. At DraftKings , 88% of the spread handle and 67% of the ML handle backs the Patriots, who have picked up a half-point at betting sites since this line peaked at -6 earlier this week.

Broncos at Jaguars

Opening Line: Broncos -1.5

Current Line: Broncos -6

The Buzz: Teddy Bridgewater, who continues to have the best record against the spread of any NFL starting QB, and the Broncos demolished Big Blue last week at MetLife Stadium in Week 1. Expect a sparse and apathetic crowd in Jacksonville. This line bulged to Denver -6.5 before eventually sliding back to -6 at DraftKings . The sportsbook reports 91% of their spread handle riding with the Broncos. Denver’s defense could make the day miserable for No. 1 overall pick Trevor Lawrence.

Bills at Dolphins

Opening Line: Bills -2.5

Current Line: Bills -3.5

Opening Total: 48.5

Current Total: 47.5

The Buzz: The line and total in this game has bounced in a narrow range at sportsbooks, driven by Buffalo’s Week 1 loss at home to Pittsburgh and Miami’s Week 1 won at New England. There’s a push among players who see the Bills rebounding and the Dolphins unable to duplicate their performance against New England. A total of 90% of the spread handle and 78% of the ML handle is backing the Bills at DraftKings .

Thursday night, the Giants kept the run of underdogs alive with a backdoor cover at +4 in their 30-29 loss to Washington.

Public Plays – Week 2

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There are handful of games in Week 2 that carry significant exposure. Virtually all the major exposure fell on the side of the sportsbooks and betting apps in Week 1. At DraftKings, there are five games with more than 88% of the spread handle on the favorite, all five of which are road teams:

Game Favorite Spread Handle
KC at BAL KC -3.5 96%
BUF at MIA BUF -3.5 91%
DEN at JAX DEN -6 90%
LAR at IND LAR -3.5 90%
NE at NYJ NE -5.5 88%

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At FanDuel, the fallout from Week 1 led to a big push on the Steelers season win total in NFL futures markets of over 8.5. The Rams absorbed the most action in the Super Bowl 56 betting market.. Eight games at the site carry an exposure of 80% or greater on the moneyline. Here’s a look:

Game FavoriteMoneyline Handle %
ATL at TB TB -720 95%
SF at PHI PHI +138 90%
TEN at SEA SEA -255 86%
KC at BAL KC -188 85%
DET at GB GB -590 85%
MIN at ARI ARI -190 85%
DAL at LAC DAL +150 82%
LAR at IND LAR -186 81%

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Odds via DraftKings and FanDuel , and are current as of publication. Check out our DraftKings sportsbook review and our FanDuel sportsbook review.

Back To The Futures

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MVP Movement

Here is where the top MVP candidates stand now vs. their NFL MVP odds heading into the season. They are ranked by their overall handle at DraftKings :

Player Team Pre-Season Current Handle %
Patrick Mahomes II KC +500 +550 13%
Josh Allen BUF +1200 +1400 12%
Aaron Rodgers GB +1000 +1600 12%
Tom Brady TB +1400 +1000 10%
Matthew Stafford LAR +1800 +800 9%
Kyler Murray ARI +1600 +1000 5%
Justin Herbert LAC +1800 +2000 5%
Carson Wentz IND +5000 +10000 4%
Russell Wilson SEA +1400 +1000 3%
Baker Mayfield CLE +3500 +3500 3%

Aaron Rodgers and Josh Allen both saw their odds soften in MVP markets after their Week 1 losses on the field. The public shifted toward Tom Brady and Matthew Stafford. Elsewhere, Rodgers fell from +1000 to +1600 at PointsBet, while Allen slid from +900 to +1400 at the same site.

NFL CHAMPION: Super Bowl 56 Odds For All 32 Teams Plus NFL Futures Odds

Offensive Rookie Of The Year Action

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All five quarterbacks taken in the first round of the NFL draft played in Week 1. Mac Jones of the Patriots, Zach Wilson of the Jets and Trevor Lawrence all started but lost outright and against the spread.

Trey Lance came in for 49ers starter Jimmy Garoppolo and turned his first NFL pass into a touchdown as the 49ers won but did not cover against the Lions. Justin Fields scored on his first run from scrimmage for the Bears subbing briefly for Andy Dalton in their 34-14 loss to the Rams.

Here’s a look at the NFL Offensive Rookie of the Year odds ahead of Week 1 and before Week 2 as posted at DraftKings :

Player Team Week 1 OddsWeek 2 Odds
Mac Jones NE +450 +350
Trevor Lawrence JAX +400 +500
Trey Lance SF +800 +700
Justin Fields CHI +650 +750
Zach Wilson NYJ +700 +750
Najee Harris PIT +1300 +800

(All odds listed current as of publication.)

About the Author

Bill Speros for Bookies.com
Bill Speros
Bill Speros is an award-winning journalist and editor whose career includes stops at USA Today Sports Network / Golfweek, Cox Media, ESPN, Orlando Sentinel and Denver Post.