Best NFL Week 4 Betting Tips: How to Bet On the NFL In The UK

By Mark Fordham Sep 26th, 2025 9:04 AM EDT

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NFL fans in the UK can get ready to lose their Thursdays, Sundays and Mondays for a few months, as the 2025 season is here! With so many games each week, it can be easy to get lost when looking to place a bet on the NFL at top UK betting sites. That's why we have put together our experts' NFL betting tips to point you in the right direction.

We've got you covered with our NFL best bets, NFL bet builders, NFL acca tips and NFL player prop tips, with the best odds from UK betting sites. Keep reading for our best NFL betting tips for this week's action.

Best NFL Week 3 Betting Tips

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NFL Best Bets

Call it whatever you like - the NAP, the lock of the week, this week's banker. Every week, we'll pick out our best bet in the NFL. While our other selections will have juicier prices, our best bet will be the selection we're most confident in. With hundreds of markets to choose from at NFL betting sites, you'll be spoilt for choice. If you're having one bet on the NFL this week, this is what we would advise it should be.

Best NFL Betting Tip for Week 4

There is a new QB in town in New York, but he is going to need to be very good to pick up anything from his first game. The Chargers have started the season in great form, three wins from three including a great performance against the Chiefs. Apart from one quarter against Dallas, the Giants offense has looked poor. So poor people are actually getting excited about a running back who just runs head first into the first opposition player he sees. The Chargers will have too much here and should probably be favourites by more than a touchdown.

Back Chargers -6.5 against the Giants at 10/11 with William Hill

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21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MI, NC, NJ, OH, PA, TN, VT, VA, WV, or WY. Must sign up by 9/30/25. Apply offer in bet slip; place $1+ American football cash wager w/ odds +300 or longer each Game Day. Wager must settle as loss to qualify for FanCash equal to the amount of losing wager (up to $100 FanCash per Game Day). Rewards expire 10/31/25. Terms, including FanCash terms apply-see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA).

NFL Acca Tips

In any given week, there can be up to 16 games taking place in the NFL. That's a lot to get your head around at new betting sites. Every week, our team of experts will pick the best NFL acca tips. Most punters choose to do their NFL accas on moneyline, handicap and total points markets, but there's no limit to what you can choose. We advise choosing an acca insurance site to give yourself a chance of getting your stake back as a free bet if only one selection lets you down.

Best NFL Acca Tip - Week 4

Are the Carolina Panthers suddenly a good team after shellacking the Atlanta Falcons 30-0? Probably not, but they are playing a Patriots team there for the taking at some wild odds. The Detroit Lions beating the Cleveland Browns doesn’t require much convincing; neither does the LA Chargers disposing of a New York Giants that will be starting the Jaxson Dart era.

The Washington Commanders should be bigger favourites, but Jayden Daniels’ status will be pushing this line much closer. He sounds confident of playing, which makes us confident to take advantage.

Back Panthers, Lions, Chargers, Commanders to win at 15/2 with BetMGM

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NFL Bet Builder Tips

The NFL is always something to look out for when browsing the best bet builder sites. A lot of lines on NFL games are priced up as pick 'ems, which isn't much use for punters looking to back something at a bigger price. With NFL bet builders, you can combine multiple selections from a range of markets on the same game and combine them into one bet. Check out our best NFL bet builder tip below.

Best NFL Bet Builder Tip - Week 4

The Colts have been the biggest surprise package of the NFL season so far. Not much was expected from the Daniel Jones-led offense, but they have averaged over 30 points per game in their three outings so far. And it has been business as usual from the Rams; Davonte Adams has seamlessly replaced Cooper Kupp, so they still have a great one-two punch with Puca Nacua. Conditions at Sofi Stadium will be perfect for both teams, so there will be no excuses for them not to put up points.

Back Over 49.5 points, Stafford over 1.5 passing touchdowns, Jones over 1.5 passing touchdowns at 10/3 with BoyleSports

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21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MI, NC, NJ, OH, PA, TN, VT, VA, WV, or WY. Must sign up by 9/30/25. Apply offer in bet slip; place $1+ American football cash wager w/ odds +300 or longer each Game Day. Wager must settle as loss to qualify for FanCash equal to the amount of losing wager (up to $100 FanCash per Game Day). Rewards expire 10/31/25. Terms, including FanCash terms apply-see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA).

Best NFL Player Prop Bets

Player props have become one of the most popular NFL markets on betting apps. With these, you can back players to have over or under a set amount of yards, receptions, rushing attempts, tackles, sacks, interceptions or anything else you can think of. Some bookies on our list of betting sites also have player milestone betting, which offers higher lines and bigger odds as a result. Here's this week's best NFL player prop bet:

Best NFL Player Prop Tip - Week 4

Bijan Robinson is something of a one-man offense for the Atlanta Falcons at the moment, with Drake London struggling. He is averaging 134 yards a game rushing and receiving. He’s taking on a Washington defense that is allowing more than 100 yards on the ground a game and is the 10th-worst receiving defense in the league at this point.

Back Bijan Robinson 125+ rushing and receiving yards at 9/5 with bet365

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21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MI, NC, NJ, OH, PA, TN, VT, VA, WV, or WY. Must sign up by 9/30/25. Apply offer in bet slip; place $1+ American football cash wager w/ odds +300 or longer each Game Day. Wager must settle as loss to qualify for FanCash equal to the amount of losing wager (up to $100 FanCash per Game Day). Rewards expire 10/31/25. Terms, including FanCash terms apply-see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA).

How to Bet on the NFL - Week 3

Our aim at Bookies.com is to give you everything you need in one place for betting on the NFL. On this page, we've provided our best NFL betting tips for the week, along with a list of new customer betting offers from top UK sites.

Once you have chosen your preferred betting site, click on the link on this page to be brought to the site. Doing this will link the welcome offer to your new account. Next, sign up by entering your details on the betting site, select a payment method and make your first deposit.

To place a bet, choose American football from the list of sports available. Go to the game you want to bet on and click on the odds beside your chosen selection. This will add it to a betslip, which will appear on the page. Enter your stake, confirm the bet and voila. All that's left to do is cheer your selection on and hopefully watch it win. Once your qualifying bet settles, you'll be eligible to receive any free bets that were part of the welcome offer.

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21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MI, NC, NJ, OH, PA, TN, VT, VA, WV, or WY. Must sign up by 9/30/25. Apply offer in bet slip; place $1+ American football cash wager w/ odds +300 or longer each Game Day. Wager must settle as loss to qualify for FanCash equal to the amount of losing wager (up to $100 FanCash per Game Day). Rewards expire 10/31/25. Terms, including FanCash terms apply-see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA).

About the Author

Mark Fordham

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Mark spent over a decade as a sports reporter and editor with Goal.com and Bleacher Report. He is now a Content Editor at Bookies.com covering all manner of sports from the Premier League and cricket to the NBA and NFL, and is our resident EPL tipster. Mark also has years of experience working with all things online casino, and knows a good one from a bad one.

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